| 摘要: |
| 目的 通过剪切波弹性成像技术（SWE）联合超声造影(CEUS)评估颈动脉斑块，探讨颈动脉斑块与急性冠脉综合征（acute coronary syndrome, ACS）的相关性。方法 选取2019年1月后入院的冠心病患者88人，其中非ST抬高型急性冠脉综合征45人为研究组（ACS组），稳定性冠心病（stable coronary heart disease，SCHD）43人为对照组。行常规血生化及颈动脉常规超声检查，然后行剪切波弹性成像技术（SWE）及超声造影评估颈动脉斑块弹性值以及造影强度。结果 Logistic回归分析显示，颈动脉斑块造影增强密度是ACS发生的独立危险因素(OR = 2.853，95％CI 0.161-7.091，P = 0.027)。斑块增强密度ACS组高于SCHD组，SWE结果示ACS组平均杨氏模量明显低于SCHD组，差异有统计学意义（P＜0.05）。结论 剪切波弹性成像技术和超声造影技术均能定量评估劲动脉斑块，两者结合更能显示斑块内部结构特征，提高对冠状动脉病变的预测价值。 |
| 关键词: 声触诊组织量化 颈动脉斑块 超声造影 急性冠脉综合征 |
| DOI： |
| 投稿时间：2021-03-21修订日期：2021-09-08 |
| 基金项目:重庆市卫生和计划生育委员会医学高端后备人才培养项目(2017HBRC010) |
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| Evaluation of the Correlation between Carotid Atherosclerotic Plaque and Acute Coronary Syndromes by CEUS combined with SWE |
| zhongshigen,zhangcuncheng,lixuelin |
| () |
| Abstract: |
| Objective To evaluate carotid plaque stability in patients with coronary artery disease, we analyze the relation between carotid atherosclerotic plaque stability and acute coronary syndrome in double-modal by using SWE (shear wave elastography) and CEUS (contrast-enhanced ultrasound). Methods A total of 88 patients with CHD were enrolled after January 2019. Patients were devided into Un-ST-elevation acute coronary syndrome group (ACS n=45) and stable coronary heart disease (SCHD n=43). Plaque hardness was measured with E-modulus in SWE and density maximum in CEUS. Blood biochemical tests were carried out. Results Logistic regression analysis showed that carotid atherosclerotic plaque enhancement density is an independent risk factor for ACS(OR=2.853，95％CI 0.161-7.091，P=0.027). There were significant differences in mean E-modulus in SWE and density maximum in CEUS between ACS group and SCHD group（P＜0.05）. The stability of carotid plaques was significantly correlated with the severity of coronary artery lesions. Conclusions Quantitative analysis of carotid artery plaques by SWE combined with CEUS are helpful to predict the severity of coronary artery lesions. |
| Key words: Elastography Carotid plaque Contrast-enhanced ultrasonography Acute coronary syndrome |
