| 摘要: |
| 目的：探讨高频超声（High-resolution ultrasonography，HRU）结合空腹血糖（Fasting Blood Glucose，FBG）、糖化血红蛋白（Glycated hemoglobin,HbAlc）对早期糖尿病正中神经（Median nerve，MN）损伤的诊断效能。方法：选取本院收治的64例早期糖尿病患者的临床资料，根据神经电生理检查（Neural electrophysiological test，NET）结果将其分为30例糖尿病周围神经病变（Diabetic peripheral neuropathy，DPN）组（DPN组），34例糖尿病非周围神经病变组（非DPN组），另选取同期32例体检健康者为对照组。对所有患者的MN均行NET、HRU检查，并行FBG、HbA1c水平检测，并比较各组之间MN的HRU特征以及FBG、HbA1c水平的差异，采用受试者工作特征（Receiver operating characteristic，ROC）曲线分析其对MN损伤的诊断效能。结果：DPN组与非DPN组、对照组中MN的HRU声像图特征、测量值以及患者的FBG、HbA1c水平差异均具有统计学意义（P<0.05）。HRU结合FBG、Hb1Ac水平诊断早期糖尿病患者MN损伤的ROC曲线下面积最大（P<0.05），且敏感度、特异度最高。结论：HRU以及FBG、Hb1Ac水平对2型糖尿病周围神经病变诊断有一定帮助，而且HRU结合FBG、Hb1Ac水平有助于提高对早期糖尿病MN损伤的诊断效能，可进一步指导临床治疗方案的选择。 |
| 关键词: 高频超声 2型糖尿病 糖尿病周围神经病变 空腹血糖 糖化血红蛋白 |
| DOI： |
| 投稿时间：2021-03-25修订日期：2021-03-25 |
| 基金项目:2018年度广东省医学科研基金立项项目（A20183375） |
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| Diagnostic value of high-frequency ultrasound combined with FBG and HbAlc in median nerve injury in early diabetes |
| Hu Hua |
| () |
| Abstract: |
| Objective: To explore the diagnostic efficacy of High-resolution ultrasonography (HRU) combined with Fasting Blood Glucose (FBG) and Glycated hemoglobin (HbAlc) for early diabetic Median nerve (MN) damage. Methods: The clinical data of 64 early diabetic patients admitted to our hospital were selected and divided into 30 diabetic peripheral neuropathy (DPN) group (DPN group) according to the results of Neural electrophysiological test (NET). 34 cases of diabetic non-peripheral neuropathy group (non-DPN group), another 32 cases of healthy people during physical examination during the same period were selected as the control group. NET and HRU examinations were performed on all patients"" MN, and FBG and HbA1c levels were detected in parallel, and the HRU characteristics of MN and the differences in FBG and HbA1c levels between the groups were compared. Receiver operating characteristic (ROC) was used. Curve analysis of its diagnostic efficacy for MN injury.Results: The differences between DPN group and non-DPN group and control group were statistically significant (P<0.05) in the HRU sonographic characteristics and measurement values of MN, as well as the patient""s FBG and HbA1c levels (P<0.05). The area under the ROC curve of HRU combined with FBG and Hb1Ac levels to diagnose MN injury in early diabetic patients was the largest (P<0.05), and the sensitivity and specificity were the highest. Conclusion: HRU, FBG and Hb1Ac levels are helpful to the diagnosis of type 2 diabetic peripheral neuropathy, and HRU combined with FBG and Hb1Ac levels can help improve the diagnostic efficiency of early diabetic MN damage, and can further guide the choice of clinical treatment options. |
| Key words: High-frequency Ultrasound Type 2 diabetes peripheral nerve disease Diabetic peripheral neuropathy Fasting Blood Glucose Glycated hemoglobin |
