| 摘要: |
| 目的：探讨下腔静脉塌陷指数及右室长轴应变与肺动脉高压相关性研究。方法：选取94例肺动脉高压患者(观察组)与35例健康体检者(对照组)的临床资料进行回顾性分析,选取时间为2018年2月至2020年5月,其中观察组根据肺动脉收缩压分为轻度组(30-49mmHg,n=32)、中度组(50-69mmHg,n=32)、重度组(≥70mmHg,n=30),对比腔静脉塌陷指数、右室长轴应变、肺动脉平均压(mPAP)、肺毛细血管阻力(PVR)、肺毛细血管楔压(PCWP),分析腔静脉塌陷指数、右室长轴应变与mPAP、PVR、PCWP的相关性,以及评估腔静脉塌陷指数、右室长轴应变诊断肺动脉高压的AUC值、敏感度、特异度、约登指数。结果：观察组的腔静脉塌陷指数、右室长轴应变、PCWP低于对照组,而mPAP、PVR高于对照组(P＜0.05)。重度组的腔静脉塌陷指数、右室长轴应变、PCWP低于轻、中度组,而mPAP、PVR高于轻、中度组(P＜0.05)。Spearman相关性显示,腔静脉塌陷指数、右室长轴应变与严重程度呈负相关(r=-796/-895,P＜0.05)。 Pearson相关性显示,腔静脉塌陷指数与PVR呈负相关(r=-0.410,P＜0.05),与PCWP呈正相关(r=0.262,P＜0.05)；右室长轴应变与PVR呈负相关(r=-0.454,P＜0.05),与PCWP呈正相关(r=0.288,P＜0.05)。ROC曲线分析显示,腔静脉塌陷指数、右室长轴应变诊断肺动脉高压的AUC值分别为(0.911、0.938,P＜0.05)。结论：下腔静脉塌陷指数、右室长轴应变与肺动脉压力呈负相关,对PAH具有重要的预测价值。 |
| 关键词: 肺动脉高压 超声 腔静脉塌陷指数 右室长轴应变 |
| DOI： |
| 投稿时间：2021-07-16修订日期：2021-09-17 |
| 基金项目: |
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| Correlation study of inferior vena cava collapse index, right ventricular long axis strain and pulmonary hypertension |
| Gao Ruitao,Zhao Baozhen,Dong Yaqing |
| () |
| Abstract: |
| Objective: To explore the correlation between the inferior vena cava collapse index and the long axis strain of the right ventricle and pulmonary hypertension.Methods: The clinical data of 94 patients with pulmonary hypertension (observation group) and 35 healthy subjects (control group) were selected for retrospective analysis. The selection time was from February 2018 to May 2020. The observation group was based on pulmonary artery systolic pressure. Divided into mild group (30-49mmHg, n=32), moderate group (50-69mmHg, n=32), severe group (≥70mmHg, n=30), and compare the vena cava collapse index and right ventricular long axis strain , Pulmonary artery mean pressure (mPAP), pulmonary capillary resistance (PVR), pulmonary capillary wedge pressure (PCWP), analyze the vena cava collapse index, the correlation between the long axis strain of the right ventricle and mPAP, PVR, PCWP, and evaluate the vena cava Collapse index, AUC value, sensitivity, specificity, and Youden index for the diagnosis of pulmonary hypertension by the long-axis strain of the right ventricle. Results: The vena cava collapse index, right ventricular long axis strain, and PCWP of the observation group were lower than those of the control group, while mPAP and PVR were higher than those of the control group (P<0.05). The vena cava collapse index, right ventricular long-axis strain, and PCWP of the severe group were lower than those of the mild and moderate groups, while mPAP and PVR were higher than those of the mild and moderate groups (P<0.05). Spearman correlation showed that the vena cava collapse index and the long axis strain of the right ventricle were negatively correlated with severity (r=-796/-895, P<0.05). Pearson correlation showed that the vena cava collapse index was negatively correlated with PVR (r=-0.410, P<0.05), and positively correlated with PCWP (r=0.262, P<0.05); the long axis strain of the right ventricle was negatively correlated with PVR ( r=-0.454, P<0.05), which was positively correlated with PCWP (r=0.288, P<0.05). ROC curve analysis showed that the AUC values of the vena cava collapse index and the long axis strain of the right ventricle to diagnose pulmonary hypertension were (0.911, 0.938, P<0.05). Conclusion: Inferior vena cava collapse index and right ventricular long axis strain are negatively correlated with pulmonary artery pressure, which have important predictive value for PAH. |
| Key words: pulmonary hypertension ultrasound vena cava collapse index right ventricular long axis strain |
