| 摘要: |
| 目的 总结肌层良恶性脂肪源性肿瘤的超声图像特征。方法 选取我院经手术病理证实的70例肌层脂肪源性肿瘤患者的临床及超声检查资料，根据病理结果分为脂肪瘤组36例和脂肪肉瘤组34例，观察并比较两组肿块的位置、最大径、边界、形态、内部回声（回声等级）、有无钙化、有无细线状分隔、无回声区、血流情况等。建立Logistic回归模型，绘制受试者工作特征曲线分析该模型鉴别肌层脂肪瘤与脂肪肉瘤的诊断效能。结果 脂肪瘤组与脂肪肉瘤组在肿块最大径、回声等级、细线状高回声及血流情况比较，差异均有统计学意义（均P＜0.05），两组间肿块位置、边界、形态、钙化、无回声情况比较差异均无统计学意义。Logistic回归分析显示，最大径（OR=1.025，P=0.005）、回声等级（OR=0.321，P=0.038）、细线状分隔（OR=0.048，P=0.001）是脂肪源性肿瘤的独立危险因素。建立的Logistic回归模型鉴别肌层脂肪瘤与脂肪肉瘤的敏感性为79%，特异性为92%，曲线下面积为0.913。结论 肌层良恶性脂肪源性肿瘤的超声表现有一定特征性，能够为临床诊断、鉴别诊断及治疗提供较重要的参考依据。 |
| 关键词: 超声检查 肌层 脂肪瘤 脂肪肉瘤 |
| DOI： |
| 投稿时间：2021-08-05修订日期：2022-03-28 |
| 基金项目: |
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| Ultrasound image analysis of benign and malignant fat-derived tumors in muscle layer |
| Mao Cuilian,Peng Xiaojing,Hu Yu,Li A o |
| (Department of Ultrasound,First Affiliated Hospital of Nanjing Medical University) |
| Abstract: |
| ABSTRACT Objective To explore the ultrasonic features of benign and malignant fat-derived tumors in muscle layer，and to improve the diagnostic accuracy of the disease.Methods The clinical and ultrasonic data of 70 patients with intramuscular fat-derived tumors confirmed by histopathologically were selected.including 36 cases of lipoma （ lipoma group ）and 34 cases of liposarcoma （ liposarcoma group）.The differences of patients with age，sex，location，tumor maximum diameter，boundary，shape，echo level，calcification，anechoic，thin line separations and blood flow grade were analyzed between lipoma group and liposarcoma group.The diagnositic model was established and Logistic regression analysis was conducted.Results There were statistical significance in the tumor maximum diameter，echo level，linear hyperechoic and blood flow grade between the lipoma group and the liposarcoma group （P＜0.05），while in the sex，age，location，boundary，shape，calcification and anechoic between the two groups was no statistically significant （P＞0.05）.Logistic regression analysis showed that the tumor maximum diameter （OR=1.025，P=0.005），echo grade （OR=0.321，P=0.038），and thin line separations（OR=0.048，P=0.001） were independent risk factors of fat-derived tumors，the sensitivity，specificity of the model in the differential diagnosis of the lipoma group and the liposarcoma group were 79%，92%，The area under ROC curve was 0.913.Conclusion The Muscular fat-derived benign and malignant tumors showed some characteristics in clinical and ultrasonic manifestations，which can provide an important reference for clinical diagnosis，differential diagnosis and treatment. |
| Key words: Ultrasonography, muscle layer , Lipoma, Liposarcoma |
