【Abstract】 Objective: To investigate the concordance between ultrasound dual imaging and ultrasound endoscopy in the re-staging of progressive gastric cancer (AGC) after neoadjuvant therapy. Methods: Retrospective analysis of medical records of 63 patients with AGC treated in our hospital from January 2018 to January 2020, who underwent dual ultrasound tracing and ultrasound endoscopy after neoadjuvant therapy, and analysis of the T-stage, lesion size and surrounding tissue invasion of patients after neoadjuvant therapy by these two examination modalities. Results: Among 63 patients with AGC, dual ultrasonography diagnosis showed 12 cases of T2 stage, 34 cases of T3 stage and 17 cases of T4 stage, while ultrasound endoscopy diagnosis showed 11 cases of T2 stage, 32 cases of T3 stage and 20 cases of T4 stage. The agreement rate between dual ultrasonography and ultrasound endoscopy for the diagnosis of T-stage after neoadjuvant therapy was 84.13% with strong agreement (Kappa=0.738). There was no statistically significant difference in the value of double ultrasonography versus ultrasound endoscopy for the assessment of right and left, longitudinal and anterior and posterior diameters of lesions after neoadjuvant treatment (P > 0.05). The diagnostic agreement between dual ultrasonography and ultrasound endoscopy on whether the transverse colon and its mesentery were invaded after neoadjuvant treatment was 79.37% and moderate (Kappa=0.471). The agreement rate between dual ultrasonography and ultrasound endoscopy for the diagnosis of liver and spleen invasion after neoadjuvant therapy was 71.43% with moderate agreement (Kappa=0.581). The concordance rate between dual ultrasonography and ultrasound endoscopy for the diagnosis of duodenal and pancreatic invasion after neoadjuvant therapy was 73.02% with moderate concordance (Kappa=0.613). Conclusion:Ultrasound dual contrast and endoscopy after AGC neoadjuvant treatment have a high consistency in T staging and lesion size, but the consistency in the assessment of tissue invasion is moderate.