Kimura disease is a rare benign and chronic infiltrative disease. The etiology is not clear. It may be related to immune disorders, allergic reactions, non-specific infections and other related [1]. The clinical manifestations are mainly chronic pain prone subcutaneous soft tissue tumors, which are common in salivary glands. The disease can occur at any age and the incidence rate of male is far higher than that of women. Kimura disease has a benign course. According to previous studies, the recurrence rate is high. Laboratory examination showed that the peripheral blood eosinophil count increased and the serum IgE level increased [2]. The specific ultrasonic manifestations of this case are: hypoechoic lesions in bilateral submandibular glands, with multiple small flake hypoechoic intervals mixed with "grid" hyperechoic, rich blood flow signals, unclear boundary between skin and medulla of lymph nodes in and around the glands, and "portal" blood flow signals. It is mainly differentiated from hemangioma in soft tissue. The ultrasonic manifestations of hemangioma are spindle, round or ovoid tumors in soft tissue, with clear or unclear boundary, uneven internal echo, mostly low echo, typical honeycomb structure can be seen, rich blood flow signals can be detected, the blood flow signals increase after the pressure of the probe is loosened, and there is no enlargement of surrounding lymph nodes. However, after the Kimura disease probe was pressurized, the mass deformation was not obvious, and the blood flow signal changed little, which can be distinguished from hemangioma. It is difficult to make a definite diagnosis of Kimura disease before operation. Ultrasound is the first choice for the diagnosis of Kimura disease and postoperative follow-up observation.