| 摘要: |
| 【摘要】目的 探讨二维斑点追踪显像技术(2D-STI)评估新生儿窒息合并心肌损害后左心室整体及局部心肌的纵向收缩功能在早期诊断窒息新生儿心肌损害中的临床价值。方法 选择2019年07月至2020年12月期间在右江民族医学院附属医院新生儿科住院的足月窒息新生儿61例，经临床确诊合并心肌损害，根据Apgar评分分为轻度组31例和重度组30例，选择同期住院出生的正常足月新生儿30例作为对照组。检测受检者的血清肌酸激酶同工酶（CK-MB）、肌钙蛋白（cTnT）、左室舒张期前后径（LVDId）、左室射血分数（LVEF）、左室短轴缩短率（LVFS）、辛普森法左室射血分数（Simpson EF）、左室三腔心整体应变（GLS-LAX）、左室四腔心整体应变（GLS-A4C）、左室两腔心整体应变（GLS-A2C）、左室整体应变（GLS-AVG）,分析GLS-AVG和CK-MB、cTnT三者的相关性。结果 三组间CK-MB和cTnT比较差异有统计学意义（P<0.05）。三组间性别、体重、胎龄均无统计学差异（P>0.05）。三组间LVDId、LVEF、LVFS、Simpson EF比较差异无统计学意义（P>0.05）。GLS-AVG与CK-MB呈负性相关（r=-0.515，P=0.000），GLS-AVG与cTnT呈负性相关（r=-0.912，P=0.000）。结论 GLS-AVG与CK-MB、cTnT具有相关性，GLS-AVG可作为窒息新生儿心肌损害早期诊断指标。 |
| 关键词: 斑点追踪技术 窒息新生儿 左心功能 心肌损害 相关性 |
| DOI： |
| 投稿时间：2021-09-09修订日期：2021-10-27 |
| 基金项目:2020年度广西高校中青年教师科研基础能力提升项目(2020KY13012)2018年百色市科学研究与技术开发计划项目(百科20184711) |
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| Evaluation of the relevance between systolic longitudinal function of the left ventricle in asphyxia newborn and myocardial damage using two-dimensional speckle tracking imaging( 2D-STI) |
| chenchengcai,lilizhen |
| () |
| Abstract: |
| 【Abstract】Objective Objective to investigate the clinical value of two-dimensional speckle tracking imaging (2D-STI) in the early diagnosis of neonatal asphyxia with myocardial damage. Methods Methods from July 2019to December 2020, 61 full-term asphyxiated newborns hospitalized in the Department of Neonatology, Affiliated Hospital of Youjiang Medical College for nationalities were selected. According to Apgar score, they were divided into mild asphyxia group (31 cases) and severe asphyxia group (30 cases). 30 normal full-term newborns hospitalized in the same period were selected as the control group. The serum creatine kinase isoenzyme (CK-MB), troponin (cTnT), left ventricular diastolic diameter (lvdid), left ventricular ejection fraction (LVEF), left ventricular short axis shortening rate (lvfs), Simpson's left ventricular ejection fraction (Simpson's EF), global strain gls-lax, gls-a4c, gls-a2c in each section were detected The correlation between gls-avg and CK-MB, cTnT was analyzed. Results There were significant differences in CK-MB and cTnT among the three groups (P < 0.05). There were no significant differences in gender, weight and gestational age among the three groups (P > 0.05). There was no significant difference in lvdid, LVEF, LVFS and Simpson EF among the three groups (P > 0.05). GLS-avg was negatively correlated with CK-MB (r = - 0.515, P = 0.000), GLS-avg was negatively correlated with cTnT (r = - 0.912, P = 0.000). Conclusion GLS-avg is highly correlated with CK-MB and cTnT. GLS-avg can be used as an early diagnostic index of myocardial damage in asphyxiated neonates. |
| Key words: speckle tracking imaging asphyxia newborns function of the left ventricle myocardial damage relevance |
