| 摘要: |
| 目的 应用三维超声斑点追踪成像(3D-STI)定量评价青年尿毒症患者肾移植术后早期左室整体应变。方法 选取成功行肾移植的青年尿毒症患者31例(肾移植组)及年龄性别相仿的健康志愿者 31例(对照组),正常对照组与肾移植组(术前、术后1月、术后3月)分别行常规超声心动图检查及3D-STI指标测量；比较各组左室整体纵向收缩期峰值应变(GLS)、左室整体径向收缩期峰值应变(GRS)、左室圆周收缩期峰值应变(GCS)和左室面积收缩期峰值应变(GAS)的差异。结果 术前肾移植组GLS、GCS、GRS、GAS低于正常对照组(P<0.05),术后一月,GLS较术前无显著差异,GCS、GRS、GAS较术前降低(P<0.05),术后三月,GLS、GCS、GRS、GAS较术前比较均升高(P<0.05)。术后三月GCS、GRS较正常对照组间无显著差异,GLS、GAS小于正常对照组(P<0.05)。结论 1、GLS、GAS是尿毒症患者心肌受损的敏感指标,GRS、GCS是维持尿毒症患者心功能的主要因素；2、青年尿毒症患者肾移植早期心脏结构和功能得到有效改善。 |
| 关键词: 三维斑点追踪 肾移植 尿毒症 左心功能 |
| DOI： |
| 投稿时间：2021-10-27修订日期：2022-03-16 |
| 基金项目: |
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| Assessment of early left heart function after kidney transplantation in young uremia patients using three-dimensional speckle-tracking echocardiographyLiao Meimei1, Guo Ruiqiang1, Zhang Long2, Chen Zhongbao2, Wang Tianyu2 |
| liaomeimei,guoruiqiang,zhanglong,chenzhongbao,wangtianyu |
| (Renmin Hospital of Wuhan University) |
| Abstract: |
| Objective To assess the early left heart function after kidney transplantation in young uremia patients using three-dimensional speckle-tracking echocardiograph. Method 31 young uremic patients who successfully underwent renal transplantation (renal transplantation group) and 31 healthy volunteers of the same age and sex (control group) were selected. Routine echocardiography and 3D-STI indexes were measured in normal control group and renal transplantation group (preoperative, 1 month and 3 months after operation); The differences of left ventricular global longitudinal systolic peak strain (GLS), left ventricular global radial systolic peak strain (GRS), left ventricular circumferential systolic peak strain (GCS) and left ventricular area systolic peak strain (GAS) were compared. Results GLS, GCS, GRS, and GAS in the kidney transplantation group before surgery were lower than those in the normal control group (P<0.05). Compared to preoperative, there was no significant difference in LVGLS one month after surgery in the transplantation group, while GCS, GRS, and GAS were lower (P<0.05); GLS, GCS, GRS, GAS were all higher three months after operation than those before operation in the transplantation group (P<0.05). Three months after operation, there was no significant difference in GCS and GRS between the normal control group, and GLS and GAS were lower than those in the normal control group (P < 0.05). Conclusion 1. GLS and GAS are sensitive indicators of myocardial damage in patients with uremia, and GRS and GCS are the main factors to maintain cardiac function in patients with uremia; 2. The structure and function of the heart in the early stage of kidney transplantation in young uremia patients have been effectively improved. |
| Key words: Three-dimensional speckle-tracking echocardiography Kidney transplantation Uremia Left heart function |
