| 摘要: |
| 目的 探讨超声引导下粗针穿刺活检（USG-CNB）诊断淋巴瘤的临床应用价值，进一步分组研究探讨USG-CNB于不同病灶情况中诊断淋巴瘤的临床应用价值。方法 回顾性分析于我院行USG-CNB和手术切除活检（SEB）的淋巴瘤患者353例，其中USG-CNB组139例，SEB组214例。结合临床表现、实验室检查、影像学检查、病理学检查及药物治疗效果得出最终诊断为诊断金标准，比较USG-CNB对不同病灶短径淋巴瘤的诊断效能，比较USG-CNB与SEB对不同亚型（霍奇金淋巴瘤和非霍奇金淋巴瘤）、部位淋巴瘤的诊断效能。结果 USG-CNB组诊断成功117例，SEB组诊断成功202例，二者诊断准确率比较（84.2% vs. 94.4%）,差异有统计学意义（P=0.003）。USG-CNB组中不同病灶短径淋巴瘤的诊断准确率比较差异均无统计学意义。USG-CNB与SEB对霍奇金淋巴瘤的诊断准确率比较（50% vs. 100%），差异有统计学意义（P＜0.001）；对非霍奇金淋巴瘤的诊断准确率比较（88.6% vs. 93.8%），差异无统计学意义。USG-CNB与SEB对浅表淋巴瘤的诊断准确率比较（83.0% vs. 93.5%），差异有统计学意义（P=0.001）；USG-CNB与SEB对深部淋巴瘤的诊断准确率比较（87.9% vs. 96.6%），差异无统计学意义。USG-CNB与SEB对浅表与深部非霍奇金淋巴瘤的诊断准确率比较差异均无统计学意义。结论 应用USG-CNB诊断淋巴瘤具有实时、快速、微创、价廉等优势，尤其对位于深部的淋巴瘤病灶的诊断价值较高。 |
| 关键词: 超声引导 粗针穿刺活检 手术切除活检 淋巴瘤 |
| DOI： |
| 投稿时间：2021-12-23修订日期：2022-06-11 |
| 基金项目: |
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| Clinical value of ultrasound guide core needle biopsy in the diagnosis of lymphoma |
| He Ling,Liu Liping,Peng Yupei,Kou Zhen,Ma Kexin |
| (The first affiliated Hospital of Chongqing Medical University) |
| Abstract: |
| Objective This study aimed to explore the clinical value of ultrasound guide core needle biopsy（USG-CNB） in the diagnosis of lymphoma.To further explore the clinical value of USG-CNB in the diagnosis of lymphoma in different lesions.Methods The clinical data of 353 patients with lymphoma who underwent USG-CNB and surgical excision biopsy (SEB) in our hospital were analyzed retrospectively. Among them，there were 139 cases of the USG-CNB group，214 cases of the SEB group.Combined with clinical manifestations, laboratory examination, imaging examination, pathological examination and drug treatment effect, the final diagnosis was obtained as the gold standard for diagnosis, the diagnostic efficacy of USG-CNB for short-diameter lymphoma of different lesions was compared, and the diagnostic efficacy of USG-CNB and SEB for different subtypes (Hodgkin's lymphoma and non-Hodgkin's lymphoma) and site lymphoma was compared.Results The diagnosis was successful in 117 cases in the USG-CNB group and 202 cases in the SEB group, and the diagnostic accuracy between the two groups was compared (84.2% vs. 94.4%), and the difference was statistically significant (P = 0.003). There was no significant difference in the diagnostic accuracy of short-diameter lymphoma with different lesions in USG-CNB group. The diagnostic accuracy of USG-CNB and SEB in Hodgkin's lymphoma was compared (50% vs. 100%), the difference was statistically significant (P ＜ 0.001). There was no significant difference in the diagnostic accuracy of non-Hodgkin's lymphoma (88.6% vs. 93.8%).There was a significant difference in the diagnostic accuracy between USG-CNB and SEB for superficial lymphoma (83.0% vs. 93.5%) (P = 0.001). There was no significant difference between USG-CNB and SEB in the diagnosis of deep lymphoma (87.9% vs. 96.6%). There was no significant difference between USG-CNB and SEB in the diagnosis of superficial and deep non-Hodgkin's lymphoma.Conclusion The application of USG-CNB in the diagnosis of lymphoma has the advantages of real-time, rapid, minimally invasive and cheap ,especially for lymphoma lesions located in the deep part. |
| Key words: Ultrasound guide Core needle biopsy Surgical excision biopsy Lymphoma |
