| 摘要: |
| 目的：应用经食管三维超声的二尖瓣定量技术分析心内结构、功能正常的二尖瓣结构参数的范围并总结其随心动周期的变化规律，以期为评估二尖瓣病变提供理论基础。
方法：收集37例心内结构、功能正常的二尖瓣食管中段2D及实时三维全容积成像，完整包括二尖瓣及主动脉瓣结构。存取动态图像后记录舒张早、中、晚期及收缩早、中、晚期共6个时相内瓣环前后径、左右径、内纤维三角、瓣叶交界距离等18个二尖瓣结构的数据，总结其参考值范围并分析其运动规律。
结果：总结出该37例研究对象二尖瓣瓣环结构的参考值范围，并发现其随心动周期呈规律性变化：瓣环前后径及左右径，瓣环面积，瓣环周长，前、后瓣环长度，内纤维三角距离，瓣叶交界距离，这些参数的最大值出现在舒张期，最小值出现在收缩期。瓣环高度，瓣环高度/左右径，非平面角度，AO-MV瓣环夹角，AO-MV中点距离，它们的最大值出现在收缩期，最小值出现在舒张期。与前面的结构不同，瓣叶3个分区的Tenting高度及Tenting面积的最大值和最小值分别出现在收缩期早期及晚期。
结论：经食管三维超声的自动定量分析系统能较为快速、直观的重建二尖瓣模型，自动测量多项结构参数。本研究通过分析各参数的最大值、最小值出现的时相，有助于加深理解二尖瓣结构的运动规律，所总结出的参考值范围对于判断二尖瓣病变提供了理论参考，为进一步研究二尖瓣病变结构的变化奠定基础。 |
| 关键词: 三维超声 经食管超声心动图 二尖瓣结构 心动周期 |
| DOI： |
| 投稿时间：2021-12-26修订日期：2022-01-18 |
| 基金项目:国家自然科学基金面上项目81773553 |
|
| A preliminary study of normal mitral valve structural parameters and their variation patterns with cardiac cycle by three-dimensional transesophageal echocardiography |
| hantao,mengxin |
| (Air Force Medical University) |
| Abstract: |
| Objective: The quantitative mitral valve technique of three-dimensional transesophageal echocardiography was applied to analyze the range of structural parameters of the mitral valve with normal intracardiac structure and function, and summarize their variation patterns with cardiac cycle in order to provide a theoretical basis for the assessment of mitral valve lesions.
Methods: 2D images and real-time 3D full-volume images of the mitral valve were collected from 37 subjects with normal intracardiac structure and function, and the images were complete including mitral and aortic valve structures. The data include 18 parameters such as the annular diameter, annular height etc. All the data were recorded in 6 time phases of early, mid, and late diastole and early, mid, and late systole. analyze these data and determine their value reference ranges and analyze their motion regularity.
Results: The reference range of mitral valve structures in the 37 subjects was summarized and found to vary regularly with cardiac cycle: some parameters have their maximum values occurring in diastole and their minimum values occurring in systole, such as anterior-posterior and left-right annular diameters, annular area, annular circumference, anterior and posterior annulus length etc. Another parameters have their maximum values occurring in systole and their minimum values occurring in diastole, such as annular height, nonplanar angle, AO-MV angle, and AO-MV midpoint distance. Unlike the previous structures, the maximum and minimum values of Tenting height and Tenting area for the 3 subdivisions of the valve leaflets appeared in early and late systole, respectively.
Conclusion: The automated quantitative analysis system of three-dimensional transesophageal echocardiography can reconstruct the mitral valve model relatively quickly and intuitively, and automatically measure several structural parameters. In this study, the time phases of the maximum and minimum values of each parameter are analyzed and helped to deepen the understanding of the mitral valve structure and its motion pattern. The range of reference values summarized in this study provides a theoretical reference for determining mitral valve lesions. and lays the foundation for further research on the structural changes of mitral valve lesions. |
| Key words: three-dimensional ultrasound, transesophageal echocardiography, mitral valve structure, Cardiac cycle |
