| 摘要: |
| 目的：探讨二维斑点追踪技术（2D-STE）评估慢性中重度主动脉瓣反流（AR）患者升主动脉的纵向力学特征变化的应用价值。
方法：连续收集慢性中重度AR患者93例为病例组，另选同期年龄、性别相匹配的健康志愿者80例为对照组。记录所有受试者性别、年龄、血压等一般临床参数，二维超声心动图测量左室相关参数、升主动脉内径（AAd）、每搏量指数（SVI）等参数。应用QLAB脱机分析软件分析受试者升主动脉前壁、后壁（AW-LS、PW-LS）及平均纵向应变（M-LS）。
结果：与对照组相比，慢性中重度AR患者升主动脉的AW-LS、PW-LS均明显减低（P＜0.001）；升主动脉的LS与升主动脉内径、收缩压、脉压、SVI和心率呈显著负相关（P＜0.001）。
结论：与健康人相比，慢性中重度AR患者加速了升主动脉的变性和硬化，慢性中重度AR患者升主动脉的纵向力学特征或许能够为手术时机的选择提供参考。 |
| 关键词: 慢性中重度主动脉瓣反流 二维斑点追踪技术 升主动脉 纵向应变 |
| DOI： |
| 投稿时间：2022-03-31修订日期：2022-08-22 |
| 基金项目:省自然基金资助项目 |
|
| Evaluation of Longitudinal Strain of Ascending Aorta in Patients with Chronic Moderate to Severe Aortic Regurgitation by Two-dimensional Speckle Tracking Echocardiography |
| Cao Siqi,Gong Min,Wang Yanli,Yu Meng,Guo Xiaoxia,Wu Jun |
| (Department of Cardiovascular Ultrasound,the Second Affiliated Hospital of Dalian Medical University,Dalian) |
| Abstract: |
| Abstract:Objective To investigate the application value of two-dimensional speckle tracking echocardiography (2D-STE) in evaluating longitudinal mechanical characteristics of ascending aorta in patients with chronic moderate to severe aortic regurgitation (AR). Methods 93 patients with chronic moderate to severe AR were continuously collected as the case group, and 80 healthy volunteers with matched age and gender were collected as the control group. General clinical parameters such as gender, age, blood pressure and so on were recorded, and left ventricle related parameters, ascending aortic diameter (AAd), stroke volume index (SVI) and so on were measured by two-dimensional echocardiography. The longitudinal strain of anterior and posterior wall of the ascending aorta were analyzed by QLAB offline analysis software, and the mean values of them were denoted as mean LS. Results Compared with the control group, AW-LS, PW-LS of ascending aorta in chronic moderate to severe AR patients were significantly decreased (P＜0.001). LS of ascending aorta was negatively correlated with AAd, systolic blood pressure, pulse pressure, SVI and heart rate (P＜0.001). Conclusion Compared with healthy people, patients with chronic moderate and severe AR have accelerated the degeneration and sclerosis of ascending aorta. The longitudinal mechanical characteristics of ascending aorta in patients with chronic moderate to severe AR may provide reference for the choice of surgical timing. |
| Key words: Chronic moderate to severe aortic regurgitation, 2D-STE, Ascending aorta, Longitudinal strain |
