| 摘要: |
| 摘 要 目的 应用三维超声斑点追踪技术（3D-STI）评估原发性干燥综合征（pSS）合并中度肺动脉高压（PAH）患者左室运动改变。方法 选取60例pSS患者作为实验组，分为无PAH组（pSS-NPAH组）30例、合并中度PAH组（pSS-PAH组）30例，同时纳入20例健康志愿者为对照组。比较三组常规二维超声心动图参数和3D-STI参数：心肌纵向应变值（GLS）?心肌圆周应变值（GCS）?心肌径向应变值（GRS）、左心室整体扭转角度峰值（LVPtw）、左心室整体扭转达峰时间（LVPtwT），通过ROC曲线分析比较GLS、GCS、GRS、LVPtw的诊断效能。结果 PSS-NPAH组与对照组比较，GLS、GCS、GRS降低，差异有统计学意义（均P＜0.05），pSS-PAH组与对照组、pSS-NPAH组比较，GLS、GCS、GRS和LVPtw降低，LVPtwT升高，差异有统计学意义（均P＜0.05），ROC曲线显示，GLS、GCS、GRS、LVPtw检测pSS合并中度PAH患者左心功能异常的曲线下面积（AUC）范围为0.833~0.935，准确性较好。结论 PSS造成心室功能受损，3D-STI可早期检测pSS合并中度PAH时左室心肌扭转运动改变和应变改变，评估左室功能受损程度。 |
| 关键词: 三维超声斑点追踪技术 原发性干燥综合征 肺动脉高压 左室 |
| DOI： |
| 投稿时间：2022-04-09修订日期：2022-08-26 |
| 基金项目:山东省医药卫生科技发展计划项目(2018WS368) |
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| Evaluation of left ventricular movement change in primary sj?gren's syndrome patients with moderate pulmonary arterial hypertention by three-dimensional speckle tracking imaging |
| liwen,suxinyue,duansujuan,malan,LIUYONG |
| () |
| Abstract: |
| ABSTRACT Objective To evaluate the left ventricular movement change in primary sj?gren's syndrome(pSS) patients with moderate pulmonary arterial hypertention(PAH) by three-dimensional speckle tracking imaging(3D-STI) technique.Methods 60 patients with pSS were divided into two groups according to pulmonary arterial hypertension:pSS-NPAH group (without PAH,30 cases) and pSS-PAH group(with moderate PAH,30 cases),other 20 healthy adults were included into control group.Compare their two-dimensional ultrasonic parameters and 3D-STI parameters:global longitudinal strain(GLS),global circumferential strain (GCS),global radial strain (GRS),left ventricular peak twist (LVPtw),time at left ventricular peak twist (LVPtwT).ROC curve was used to analyze the sensitivity and specificity of three-dimensional parameters in the diagnosis of left ventricular movement change of pSS patients with moderate PAH.Results Compared with control group,GLS、GCS、GRS were significantly decreased in pSS-NPAH group(all P <0.05),compared with control group and pSS-NPAH group,GLS、GCS、GRS、LVPtw were significantly decreased and LVPtwT were significantly increased in pSS-PAH group(all P <0.05).ROC curve analysis showed that the area under the curve of three-dimensional parameters were 0.833-0.935, the accuracy was good.Conclusion PSS can impaire ventricular function,3D-STI can be used to evaluate left ventricular systolic function in pSS patients with moderate PAH. |
| Key words: Three-dimensional speckletracking imaging Primary sj?gren's syndrome Pulmonary arterial hypertension Left ventricular function |
