Abstract:Objective To explore the value of noninvasive myocardial work(MW) technique to evaluate the right ventricular function in patients with pulmonary hypertension (PH). Methods 112 patients with PH were selected, according to pulmonary arterial systolic pressure(PASP), 33 patients were divided into mild group, 45 in moderate group and 34 in severe group, meanwhile 44 healthy volunteers were selected as control group. Conventional echocardiographic parameters were measured, and the right ventricular myocardial work(RVMW) parameters were obtained using the noninvasive myocardial work technique,including right ventricular global work index(RVGWI),right ventricular global constructive work(RVGCW),right ventricular global wasted work (RVGWW),right ventricular global work efficiency(RVGWE).Differences between the parameters were compared between the four groups, and the correlation of right ventricular myocardial work(RVMW) parameters with conventional ultrasound right ventricular function parameters were also analyzed. Results RVGWI, RVGCW, and RVGWW gradually increased with increasing pulmonary arterial pressure, while RVGWE gradually decreased with increasing pulmonary arterial pressure.The differences of RVGWI and RVGCW in each group were statistically significant(P<0.05).The difference of RVGWE was statistically significant between severe and the remaining three groups(P<0.05).There was a correlation between the RVMW parameters and the conventional right ventricular function parameters(P<0.01). Conclusion Noninvasive RVMW allows for a quantitative assessment of RV function in patients with different grades of PH.