| 摘要: |
| 摘要 目的 观察焦磷酸钙沉积病（CPPD）与痛风性关节炎（GA）的超声表现，探讨超声在鉴别CPPD与GA中的应用价值。方法 收集我院82例CPPD和61例GA患者的一般资料和超声表现，比较两组差异性。结果 CPPD与GA在好发年龄及性别不同（P＜0.05），CPPD女性好发，GA男性好发，CPDD老年患者好发(＞65岁)。CPPD最常见部位为膝关节，GA最常见部位为第一跖趾关节。GA组多关节受累发生率多于CPPD组，但CPPD更具有对称性受累趋势（P＜0.05）。CPDD组软骨钙化发生率更高，GA双轨征、骨侵蚀、痛风石、肌腱及韧带内强回声发生率更高（P均＜0.05），而滑膜内强回声发生率两组差异无统计学意义（P＞0.05）。两组患者半月板退行性变、软骨损伤、骨皮质不规则、滑囊炎、滑膜增厚、软组织肿胀发生率差异有统计学意义（P均＜0.05），而关节积液、骨赘形成、腱鞘炎、腱鞘积液、肌腱病发生率无明显差异（P＞0.05）。结论 超声可显示CPPD与GA关节的病理改变与结构异常，为临床诊断及鉴别提供参考。 |
| 关键词: 焦磷酸钙沉积病 假性痛风 软骨钙化 痛风 肌骨超声 |
| DOI： |
| 投稿时间：2022-05-01修订日期：2022-06-19 |
| 基金项目:国家自然科学基金项目（面上项目，重点项目，重大项目） |
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| Application of Ultrasound in Differentiating Calcium Pyrophosphate Deposition Disease from Gouty Arthritis |
| weiminjie,zhanghua,sunyue,xufengwei,ranhaitao |
| (the second affiliated hospital of Chongqing medical university) |
| Abstract: |
| Abstract Objective To observe the ultrasound manifestations of calcium pyrophosphate deposition disease (CPPD) and gouty arthritis (GA), and to explore the application value of ultrasound in differentiating CPPD from GA. Methods The general data and ultrasound findings of 82 CPPD patients and 61 GA patients in our hospital were collected, and the differences between the two groups were compared. Results CPPD and GA were different in age and gender (P<0.05), women with CPPD were more common, men with GA were more common, and elderly patients with CPDD (>65 years old). The most common site of CPPD is the knee joint, and the most common site of GA is the first metatarsophalangeal joint. The number of people involved in polyarticular joints in GA group was more than that in CPPD group, but CPPD had a more symmetrical tendency of involvement (P<0.05). The CPPD group had a higher incidence of cartilage calcification, a higher incidence of GA double-track sign, bone erosion, tophi, tendon and ligament hyperechoic incidence (P < 0.05), but no significant difference in synovial hyperechoic incidence between the two groups(P>0.05).The incidences of meniscus degeneration, cartilage damage, bone cortical irregularity, bursitis, synovial thickening, and soft tissue swelling were significantly different between the two groups (P< 0.05) , tenosynovitis, hydrocele, and tendinopathy had no significant difference (P>0.05). Conclusion Ultrasound can clearly show the structural abnormalities of CPPD and GA joints, which can provide reference for clinical diagnosis. |
| Key words: Calcium pyrophosphate deposition disease Pseudogout Chondrocalcinosis Gout Musculoskeletal Ultrasound |
