| 摘要: |
| 目的 探讨超声造影(CEUS)评价糖尿病足背部足拇短伸肌微循环的应用价值。 方法 收集正常对照组25例、2型糖尿病(DM)组14例及2型糖尿病合并微血管病变(DM+MC)组16例。利用超声造影(CEUS)测量足拇短伸肌的血流灌注情况,获取造影剂到达时间(AT)、自跗外侧动脉到达足拇短伸肌时间(ΔAT)、峰值强度(PI)和实际增强强度(ΔPI)等灌注参数,各组造影参数有差异者进行事后两两比较；以DM+MC为判定标准,探讨造影参数对早期微循环障碍的诊断效能。 结果 三组CEUS的PI及ΔPI两两比较差异均有统计学意义(P均＜0.05),三组CEUS的AT及ΔAT在正常组与DM组之间差异没有统计学意义(P＞0.05),在DM组与DM+MC组、正常组与DM+MC组之间的差异有统计学意义(P＜0.05),以临床诊断DM+MC为结果,CEUS的ΔAT(AUC 0.989)、ΔPI(AUC 0.954)诊断效能最佳。 结论 超声造影可以评价糖尿病足背部足拇短伸肌的微循环情况,ΔPI及ΔAT可为临床早期发现糖尿病足提供一定的诊断依据。 |
| 关键词: 糖尿病,微循环,骨骼肌,超声造影 |
| DOI： |
| 投稿时间：2022-06-13修订日期：2022-06-29 |
| 基金项目:泉州科技局计划项目(2021N042S) |
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| The value of contrast-enhanced ultrasonography in evaluating microcirculation of extensor pollicis brevis in the dorsum of foot in diabetic patients |
| YAN Fuqiang,SHI Yingying,LIN Jinmiao,HUANG Shanshan,CAI Mingli,LI Meirong,LYU Guorong |
| (Jinjiang Municipal HospitalShanghai Sixth People,s Hospital Fujian Campus;Quanzhou Medical College Provincial Collaborative Innovation Center for Maternal and Infant Health Service Application Technology) |
| Abstract: |
| Objective To evaluate the value of contrast-enhanced ultrasound (CEUS) in evaluating skeletal muscle microcirculation in Diabetic Foot Dorsum. Method 25 cases of the normal control group, 14 cases of type 2 Diabetes Mellitus (DM) group, and 16 cases of type 2 diabetes mellitus with microangiopathy (DM+MC) group were collected. The blood perfusion of the extensor pollicis brevis was measured by contrast-enhanced ultrasound (CEUS), and the perfusion parameters such as the time of arrival of contrast medium (AT), the time from the lateral tarsal artery to the extensor pollicis Brevis (ΔAT), the peak intensity (PI) and the actual enhancement intensity (ΔPI) were obtained, the patients with different angiographic parameters were compared with each other. Using DM+MC as the criterion, the diagnostic efficacy of angiography parameters in early microcirculation disorders was investigated. Results The difference between PI and ΔPI of CEUS in each group was statistically significant (P<0.05). There was no significant difference in AT and ΔAT between normal group and DM group (P>0.05), but there was significant difference in AT and ΔAT between DM group and DM+MC group, normal group and DM+MC group (P<0.05). The clinical diagnosis of DM+MC showed that ΔAT (AUC 0.989) and ΔPI (AUC 0.954) of CEUS were the best. Conclusion CEUS can evaluate the microcirculation of the skeletal muscle of the dorsum of the diabetic foot. The parameters ΔAT and ΔPI can provide reliable diagnostic information for the early detection of the microcirculation disturbance of the skeletal muscle of Type 2 diabetic patients. |
| Key words: Diabetes mellitus,Microcirculation,Skeletal muscle,Contrast-enhanced ultrasound |
