超声剪切波弹性成像技术用于检测眼部及眼周组织弹性参数的重复性研究
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上海市第一人民医院

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Reliability of shear wave elastography in evaluation on ocular and periocular tissues
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    摘要:

    目的:利用剪切波弹性成像(SWE)技术检测球后壁视网膜-脉络膜-巩膜复合体、视神经、球后脂肪垫和眼肌组织的弹性参数,并评价测量结果的可重复性。方法:选取健康成年志愿者33名,屈光近视者52名,利用SWE技术,由两名检查者于上午同时及10min后测量眼部视网膜-脉络膜-巩膜球后壁复合体、视神经、球后脂肪垫、内直肌、外直肌的弹性参数(Emean),并评价组间(不同检查者同一时间)的测量一致性。同一检测者于同日上、下午及一周后重复测量同一患者眼部弹性参数,评价组内(同一检查者不同时间)测量的一致性。结果:①同一检查者同一天两次测量值Emean差异无统计学意义(p>0.05),球后壁视网膜-脉络膜-巩膜复合体、视神经、球后脂肪垫、内直肌、外直肌Emean值的ICC值分别为0.82、0.85、0.86、0.83、0.84,表明组内重复性较好;②同一检查者一周前后的两次测量值Emean差异无统计学意义(p>0.05),球后壁视网膜-脉络膜-巩膜复合体、视神经、球后脂肪垫、内直肌、外直肌值的Emean值的ICC分别为0.79、0.82、0.82、0.80、0.78,组内重复性好;③两位检查者同一时间对相同患者的测量值Emean差异无统计学意义(p>0.05),ICC分别为0.71、0.75、0.79、0.73、0.75,组间重复性好。Blant-Altman分析法显示组内及组间SWE技术测量值具有良好一致性。结论:SWE可定量获取球后壁视网膜-脉络膜-巩膜复合体、视神经、球后脂肪垫、内直肌、外直肌值的杨氏模量值,且重复性好。

    Abstract:

    Objective: To assess the reliability of shear wave elastography (SWE) in evaluation on ocular structure of adult. Methods: Totally 33 healthy adult volunteers and 52 refractive myopia underwent SWE of eye region by different inspectors or same inspector in different time points. retina-choroid-sclera complex, optic nerve, retrobulbar fat tissue, internal rectus muscle and external rectus [ 通讯作者:?张志华,吴蓉 电子信箱:jundesan@163.com,wurong7111@163.com。 作者简介:李芳(1994—),女,硕士;电子信箱: 2403338915@qq.com。 ]muscle were examined ,and the intra-observer and inter-observer reproducibility were assessed. Results: Paired test showed no significant difference between the two measured values made by same inspectors on the same day (P>0.05), intra-class correlation coefficient(ICC) values of retina-choroid-sclera complex, optic nerve, retrobulbar fat tissue, Internal rectus muscle and external rectus muscle was 0.82、0.85、0.86、0.83、0.84, respectively., indicating very good reproducibility. Paired test showed no significant difference between the two measured values made by same inspectors on the different days (P>0.05), the intra-class ICC values of retina-choroid-sclera complex, optic nerve, retrobulbar fat tissue, Internal rectus muscle and external rectus muscle was 0.79、0.82、0.82、0.80、0.78, respectively., indicating very good reproducibility. Paired test showed no significant difference between the two measured values made by different inspectors (P>0.05), the intra-class correlation coefficient(ICC) values of retina-choroid-sclera complex, optic nerve, retrobulbar fat tissue, Internal rectus muscle and external rectus muscle was 0.71、0.75、0.79、0.73、0.75, respectively., indicating very good reproducibility. Conclusion: SWE has good repeatability to obtain retina-choroid-sclera complex, optic nerve, retrobulbar fat tissue, Internal rectus muscle and external rectus muscle.

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李芳,张志华,吴蓉,陈静,姚明华,马骥.超声剪切波弹性成像技术用于检测眼部及眼周组织弹性参数的重复性研究[J].临床超声医学杂志,2023,25(2):

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  • 收稿日期:2022-08-02
  • 最后修改日期:2022-08-14
  • 录用日期:2022-08-15
  • 在线发布日期: 2023-03-06
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