Objective To evaluate the right ventricular systolic function before and after dialysis in uremic patients with preserved left ventricular ejection fraction(LVEF) by using two-dimensional speckle tracking imaging(2D-STI) and right ventricular quantitative analysis system. Methods 40 patients with uremia diagnosed in the nephrology department of our hospital and undergoing regular hemodialysis were selected as the hemodialysis group.They were divided into pre dialysis and post dialysis groups.Another 35 healthy people were selected as the control group.Left ventricular ejection fraction(LVEF),right ventricular end diastolic diameter(RVEDD),tricuspid annular systolic peak flow velocity(S’),tricuspid annular plane systolic excursion(TAPSE),FAC(fractional area change) were measured by conventional echocardiography;right ventricular global longitudinal strain(RVGLS),right ventricular free wall longitudinal strain(RVFWLS) and right ventricular septal longitudinal strain(RVSLS) were measured by two-dimensional speckle tracking imaging;right ventricular end diastolic volume(RVEDV),right ventricular end systolic volume(RVESV) and right ventricular ejection fraction(RVEF) were measured by the right ventricular quantitative analysis system.Compare the differences between the above groups of parameters.Results Compared with the normal control group,the values of RVEDV and RVESV in uremic patients were increased before and after dialysis,and the values of LVEF,RVGLS,RVFWLS, RVSLS, TAPSE, FAC and RVEF were decreased(P<0.05);There was no significant difference in RVEDD and S’ between uremic patients before and after dialysis(P>0.05).Compared with the patients in the dialysis group before dialysis,the values of RVESV and RVEDV after dialysis were decreased,and the values of RVGLS,RVFWLS,RVSLS and RVEF were increased,with statistical significance(P<0.05);There was no significant difference in TAPSE and FAC after dialysis(P>0.05).In the correlation analysis,the absolute values of RVEF and RVGLS,RVFWLS and RVSLS were positively correlated,and the correlation coefficients were 0.683,0.702 and 0.476 respectively.Conclusion Two-dimensional speckle tracking imaging combined with right ventricular quantitative analysis system can evaluate the right ventricular systolic function before and after dialysis in uremic patients with preserved LVEF.