| 摘要: |
| 目的 探讨子宫内膜及子宫内膜-肌层交界区（EMI）超声参数对体外受精-胚胎移植（IVF-ET）患者妊娠结局的预测价值。方法 回顾性研究于本院生殖医学科进行IVF-ET的不孕妇女112例，在ET日对所有患者进行子宫内膜及EMI形态和血流监测，根据是否妊娠将其分为妊娠组和未妊娠组，比较两组间各参数的差异，并评价EMI超声参数对IVF-ET妊娠结局的预测价值。结果 两组患者EMI平均厚度、EMI形态、EMI容积、内膜VI、内膜FI、内膜VFI差异均有统计学意义（P均＜0.05）。其中内膜FI、EMI平均厚度和EMI形态是妊娠结局的独立影响因素，以此建立预测模型：Logit（P）=0.227×内膜FI+1.608×EMI平均厚度-1.056×EMI形态-8.315，该模型经评估后对妊娠结局预测效能良好。结论 子宫内膜及EMI超声参数对IVF-ET患者妊娠结局有预测价值。 |
| 关键词: 子宫内膜-肌层交界区 体外受精-胚胎移植 三维能量多普勒超声 妊娠结局 预测模型 |
| DOI： |
| 投稿时间：2022-08-25修订日期：2023-02-27 |
| 基金项目:宜昌市医疗卫生科研项目(A22-2-056) |
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| Predictive value of ultrasonographic parameters of endometrium and endometrial-myometrial interface for IVF-ET pregnancy outcomes |
| Lu Jia,Hu Bing |
| (Affiliated Renhe Hospital of China Three Gorges University) |
| Abstract: |
| Purpose To investigate the predictive value of endometrium and endometrial-myometrial interface (EMI) ultrasound parameters for pregnancy outcomes of in vitro fertilization - embryo transfer (IVF-ET) patients. Methods A retrospective study was conducted on 112 infertile women who received IVF-ET in Reproductive Medicine Department of our hospital. The routine ultrasound examination and three-dimensional power doppler ultrasound (3D-PDUS) were used on those patients to monitor the endometrium and EMI morphology and blood flow on ET day. Subsequently, all of the patients were divided into two groups respectively correspond to pregnant group and non-pregnant group according to whether they were pregnant or not. Therefore, the differences of two groups can be compared with, and finally the predictive value of EMI ultrasound parameters for IVF-ET pregnancy outcome was evaluated. Results The average EMI thickness, EMI morphology, EMI volume, intima VI, intima FI and intima VFI of two groups had statistical significance (P < 0.05). The endometrial FI, average EMI thickness and EMI morphology were independent influencing factors of pregnancy outcome, hence, a prediction model can be built as follows: Logit (P) = 0.227 × endometrial FI + 1.608 × average EMI thickness - 1.056 × EMI morphology - 8.315. After evaluation, this model had a good predictive effect on pregnancy outcome. Conclusion Endometrium and EMI ultrasound parameters have predictive value for the pregnancy outcome of IVF-ET patients. |
| Key words: endometrial-myometrial interface in vitro fertilization - embryo transfer three-dimensional power doppler ultrasound pregnancy outcomes prediction model |
