| 摘要: |
| 目的：分析急性ST段抬高心肌梗死(STEMI)患者治疗后左心功能、左室重构评估中无创左室压力-应变环(LV-PSL)的临床价值。方法：选定2018年10月至2019年9月接诊的90例STEMI患者作为观察组,选定同期体检中心90例健康体检者作为对比组,检测、比较两组左心功能指标、左室重构指标以及左室整体纵向应变率(GLS),通过LV-PSL检查测量左室心肌做功指标,比较两组左室心肌做功指标,比较单支、多支冠脉狭窄组左心功能、左室重构指标、GLS、左室心肌做功指标,Spearman相关性分析左室心肌做功指标与GLS、左室射血分数(LVEF)的相关性。结果：观察组左室收缩末期容积(LVESV)、左室舒张末期容积(LVEDV)、整体无效做功(GWW)术前及术后3d均高于对比组,观察组术前及术后3dLVEF、GLS、整体做功效率(GWE)、整体做功指数(GWI)、整体有效做功(GCW)均低于对比组,P＜0.05(差异均具有统计学意义),观察组LVEDV、LVESV、GWW术后3d均低于术前,观察组LVEF、GLS、GWE、GCW、GWI术后3d均高于术前,P＜0.05(差异均具有统计学意义)。多支冠脉狭窄组术前及术后3dLVEDV、LVESV、GWW均高于单支冠脉狭窄组,多支冠脉狭窄组术前及术后3dLVEF、GLS、GWE、GCW、GWI均低于单支冠脉狭窄组,P＜0.05(差异均具有统计学意义)。GWW与GLS、LVEF均呈负相关性,GWE、GCW、GWI与GLS、LVEF均呈正相关性,P＜0.05(差异均具有统计学意义)。结论：STEMI患者LV-PSL参数与GLS、LVEF存在一定相关性,通过LV-PSL检查,可准确评估患者左心功能、左室重构,具有一定的临床价值。 |
| 关键词: 无创左室压力-应变环 急性ST段抬高心肌梗死 左心功能 左室重构 |
| DOI： |
| 投稿时间：2022-09-29修订日期：2022-10-13 |
| 基金项目: |
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| Clinical value of non-invasive left ventricular pressure-strain loop in the assessment of left ventricular function and left ventricular remodeling in patients with STEMI |
| liupei,yangrong |
| () |
| Abstract: |
| Objective: To analyze the clinical value of the noninvasive left ventricular pressure-strain ring (LV-PSL) in the evaluation of left ventricular pressure-strain ring (LV-PSL) after treatment of patients with acute ST-segment elevation myocardial infarction (STEMI). Methods: 90 patients with STEMI who were treated from October 2018 to September 2019 were selected as the observation group, and 90 healthy examinees from the physical examination center in the same period were selected as the comparison group, and the left heart function index, left ventricular reconstruction index and left ventricular overall longitudinal response rate (GLS) were detected and compared, the left ventricular myocardial work function index (GLS) was measured by LV-PSL examination, the left ventricular myocardial work function index was compared between the two groups, and the left ventricular remodeling index, left ventricular remodeling index, GLS, Left ventricular myocardial work indicators, Spearman correlation analysis of left ventricular myocardial work indicators and GLS, left ventricular ejection fraction (LVEF) correlation. Results: The left ventricular end-systolic volume (LVESV), left ventricular end-diastolic volume (LVEDV), and global invalid work (GWW) in the observation group were higher than those in the control group before and 3 days after operation. Work efficiency (GWE), overall work index (GWI), and overall effective work (GCW) were all lower than those in the control group, P＜0.05 (all differences were statistically significant). Before operation, the LVEF, GLS, GWE, GCW and GWI of observation group were higher than those before operation 3 days after operation, P<0.05 (the differences were all statistically significant). The preoperative and postoperative 3dLVEDV, LVESV, and GWW of the multivessel coronary stenosis group were higher than those of the single coronary stenosis group, and the preoperative and postoperative 3dLVEF, GLS, GWE, GCW, and GWI of the multivessel coronary stenosis group were lower than those of the single coronary stenosis group. Coronary artery stenosis group, P<0.05 (all differences were statistically significant). GWW was negatively correlated with GLS and LVEF, and GWE, GCW and GWI were positively correlated with GLS and LVEF, P<0.05 (all differences were statistically significant). Conclusion: Lv-PSL parameters in STEMI patients have a certain correlation with GLS and LVEF, and LV-PSL examination can accurately assess the left heart function and left ventricular remodeling of patients through LV-PSL examination, which has certain clinical value. |
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