| 摘要: |
| 目的 探讨左室压力-应变环技术定量评估妊娠期高血压疾病患者左室功能的临床价值。方法 选取38例妊娠期高血压疾病患者（病例组）和孕龄与之匹配的健康孕妇42例（对照组），均行常规超声心动图检查，并应用左室压力-应变环技术测量左室整体纵向应变（GLS）、心肌整体做功指数（GWI）、整体有用功（GCW）、整体无用功（GWW）及整体做功效率（GWE），比较两组一般资料、常规超声心动图参数及心肌做功参数的差异；采用Spearman相关性分析心肌做功参数与收缩压和舒张压的相关性；绘制受试者工作特征（ROC）曲线分析各参数评估妊娠期高血压疾病患者心功能的诊断效能。结果 与对照组比较，病例组收缩压、舒张压、LAD、IVSD、LVPWD、GWI、GCW、GWW均增高，GWE、GLS均降低，差异均有统计学意义（均P＜0.05）。相关性分析显示，GWI、GCW、GWW与收缩压、舒张压均呈正相关，GWE、GLS与收缩压、舒张压均呈负相关（均P＜0.05）。ROC曲线分析显示，心肌做功参数GWI、GCW和GWW诊断妊娠期高血压疾病患者左心室功能改变的灵敏度及特异度均明显高于GLS和左室射血分数，尤以GCW和GWW的诊断效能最高。结论 左室压力-应变环技术在评估妊娠期高血压疾病患者左室早期心肌损害方面具有一定的价值。 |
| 关键词: 超声心动描记术 压力-应变环 妊娠期高血压疾病 收缩功能，心室，左 |
| DOI： |
| 投稿时间：2022-11-23修订日期：2023-05-30 |
| 基金项目:2021年度襄阳市医疗卫生领域科技计划项目（2021ZD16） |
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| Assessment of left ventricular function in patients with hypertensive disorder complicating pregnancy by left ventricular pressure-strain loop technology |
| he mei ling,jia chun lian,xie man ying,wang wei,gan ling |
| () |
| Abstract: |
| Objective Exploring the clinical value of quantitative assessment of left ventricular function in patients with hypertensive disorder complicating pregnancy by left ventricular pressure-strain loop technology. Methods 38 patients with hypertensive disorder complicating pregnancy (case group) and 42 healthy pregnant women of matched gestational age (control group) were selected for routine echocardiography examination. Left ventricular pressure-strain loop technology was used to measure left ventricular global longitudinal strain (GLS), myocardial global work index (GWI), global constructive work (GCW), global wasted work (GWW), and global work efficiency (GWE). The general data of the two groups were compared differences in conventional echocardiographic parameters and myocardial work parameters; Using Spearman correlation analysis to analyze the correlation between myocardial work parameters and systolic and diastolic blood pressure; Drawing a receiver operating characteristic (ROC) curve to analyze the diagnostic efficacy of various parameters in evaluating cardiac function in patients with hypertensive disorder complicating pregnancy. Results Compared with the control group, the systolic blood pressure, diastolic blood pressure, LAD, IVSD, LVPWD, GWI, GCW, and GWW in the case group increased, while GWE and GLS decreased, with statistical significance (all P<0.05). Correlation analysis showed that GWI, GCW, GWW were positively correlated with systolic and diastolic blood pressure, while GWE and GLS were negatively correlated with systolic and diastolic blood pressure (all P<0.05). ROC curve analysis shows that the sensitivity and specificity of myocardial work parameters GWI, GCW, and GWW in diagnosing left ventricular function changes in patients with hypertensive disorder complicating pregnancy are significantly higher than GLS and left ventricular ejection fraction, with GCW and GWW having the highest diagnostic efficacy.Conclusion The left ventricular pressure-strain loop technique has certain value in evaluating early left ventricular myocardial damage in patients with hypertensive disorder complicating pregnancy. |
| Key words: Echocardiography Pressure-strain loop Hypertensive disorder complicating pregnancy Systolic function,Ventricular, Left |
