| 摘要: |
| 目的：探析超声弹性成像对下肢深静脉血栓形成分期中的诊断效能。方法：选择2020年1月-2022年6月，本院收治的110例下肢深静脉血栓患者（观察组）和同期100例健康体检者（对照组）作为研究对象，均接受超声弹性成像检查。比较两组的超声弹性成像检查结果，Logistic回归分析法探析超声弹性成像各项检查指标与下肢深静脉血栓分期的关系，Pearson相关分析法探析弹性成像与实验室相关参数的关系，绘制受试者工作特征（ROC）曲线分析超声弹性成像在下肢深静脉血栓形成分期中的诊断效能。结果：观察组血栓检出人数占比及超声弹性评分均高于对照组，差异有统计学意义（P<0.05）。急性期患者的超声弹性评分、杨氏模量平均值低于亚急性期、慢性期；Logistic回归分析得，超声弹性评分、杨氏模量平均值升高是下肢深静脉血栓发展成慢性期的影响因素（P<0.05）。Pearson相关性得，超声弹性评分与aPTT、PT、Fbg呈负相关（r=-0.411、-0.484、-0.667，P<0.05）；杨氏模量平均值与aPTT、PT、Fbg呈负相关（r=-0.426、-0.506、-0.712，P<0.05）。ROC曲线分析得，超声弹性成像（超声弹性评分联合杨氏模量平均值）诊断下肢深静脉血栓形成分期的AUC（0.891，95%CI:0.795~0.987）最大，灵敏度、特异度分别为93.33%、95.00%（P<0.05）。 |
| 关键词: 下肢深静脉血栓 分期 超声弹性成像 血小板 凝血功能 效能 |
| DOI： |
| 投稿时间：2022-12-21修订日期：2023-02-04 |
| 基金项目: |
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| Diagnostic efficacy of ultrasound elastography in staging deep venous thrombosis of lower extremities |
| liuqi,guoruijun |
| () |
| Abstract: |
| Objective: To explore the diagnostic efficacy of ultrasound elastography in the staging of deep venous thrombosis of lower extremities. Methods: A total of 110 patients with deep venous thrombosis of lower limbs admitted to our hospital from January 2020 to June 2022 (observation group) and 100 healthy subjects (control group) during the same period were selected as the study objects, and all of them received ultrasound elastography examination. The results of ultrasonic elastic imaging were compared between the two groups. Logistic regression analysis was used to analyze the relationship between various indicators of ultrasonic elastic imaging and the staging of lower extremity deep vein thrombosis, and Pearson correlation analysis was used to analyze the relationship between elastic imaging and laboratory parameters. Receiver operating characteristic (ROC) curve was plotted to analyze the diagnostic efficacy of ultrasound elastography in staging of deep venous thrombosis of lower extremities. Results: The proportion of thrombus detection and ultrasound elasticity score in the observation group were higher than those in the control group, and the differences were statistically significant (P<0.05). The mean value of ultrasonic elasticity score and Young''s modulus of patients in acute stage were lower than those in subacute stage and chronic stage. Logistic regression analysis showed that the increase of ultrasonic elasticity score and mean Young''s modulus were the influencing factors for the development of lower limb deep vein thrombosis in chronic stage (P<0.05). Pearson correlation showed that the ultrasonic elasticity score was negatively correlated with aPTT, PT and Fbg (r=-0.411, -0.484, -0.667, P<0.05). The mean value of Young''s modulus was negatively correlated with aPTT, PT and Fbg (r=-0.426, -0.506, -0.712, P<0.05). According to the ROC curve analysis, the AUC (0.891, 95%CI:0.795~0.987) of ultrasonic elastic imaging (ultrasonic elastic score combined with the mean value of Young''s modulus) in diagnosing the stage of deep vein thrombosis of lower limbs was the largest, and the sensitivity and specificity were 93.33% and 95.00%, respectively(P<0.05). |
| Key words: lower extremity deep vein thrombosis stage ultrasonic elastography platelets coagulation function efficiency |
