Mitral regurgitation (MR) is one of the most common valvular diseases and its incidence is increasing. Echocardiography is the first choice for evaluating MR with the advantages of non-invasive, radiation-free, easy to perform and inexpensive. In recent years, artificial intelligence (AI) technology has been making breakthroughs and is widely used in various majors. The combination of AI and echocardiography has shown its unique value in the whole process of MR diagnosis, treatment and follow-up.