| 摘要: |
| 目的 应用血流向量成像（VFM）技术评价肥厚型心肌病（HCM）和高血压性左室肥厚（H-LVH）患者左心室收缩期血流流场变化及差异。 方法 选取HCM患者25例及H-LVH患者24例，另选取35例健康成人为正常对照组，计算等容收缩期及射血期平均能量损耗（IVC-EL, Ej-EL）、能量效率（IVC-EE, Ej-EE）、循环值（IVC-cir, Ej-cir）及涡旋面积（IVC-vor-area, Ej-vor-area）；另应用二维斑点追踪技术分析整体纵向应变（GLS），间隔纵向应变（IVS-LS）及后侧壁纵向应变（PLW-LS）。结果 ① 与对照组比较，HCM及H-LVH组GLS减低， IVC-EL、Ej-EL增加；与对照组及H-LVH组比较，HCM组Ej-EE增加， IVC-vor-area、Ej-vor-area、IVS-LS减小（P<0.05）。 ② “反向涡流”在HCM组更常见（HCM 88% vs H-LVH 16.7%，P<0.05）。③多元线性回归分析显示IVC-vor-area和GLS可以独立预测Ej-EE。结论 收缩期血流EE及涡流参数可以反映HCM及H-LVH左心室收缩期异常血流动力学及差异。 |
| 关键词: 肥厚型心肌病 高血压性左室肥厚 涡旋 能量效率 |
| DOI： |
| 投稿时间：2023-01-17修订日期：2023-03-09 |
| 基金项目:河北省卫生健康委青年科技课题(20210496) |
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| Vector Flow Mapping Evaluation on Changes of Left Ventricular Systolic Fluid in Patients with Hypertrophic Cardiomyopathy and Hypertensive Left Ventricular Hypertrophy |
| Wang Wei,Wang Yueheng,Zhou Jinling,Bai Hui,Cui Lingmei,Du hong hui |
| (The Second Hospital of He bei Medical University) |
| Abstract: |
| Objective To assess the changes and differences of left ventricular systolic blood flow field in hypertrophic cardiomyopathy (HCM) and hypertensive left ventricular hypertrophy (H-LVH) patients. Methods 25 HCM patients and 24 H-LVH patients were selected in this study, 35 healthy adults were enrolled as control group. The average energy loss, energy efficiency, intra-ventricular vortex circulation and area during isovolumic contraction and ejection stages were calculated, namely IVC-EL, Ej-EL; IVC-EE, Ej-EE; IVC-cir, Ej-cir; IVC-vor-area, Ej-vor-area. The total longitudinal strain (GLS), interventricular septal strain (IVS-LS) and posterior lateral wall strain (PLW-LS) were analyzed by two-dimensional speckle tracking technique. Results ① Compared to the control group, GLS decreased and IVC-EL and Ej-EL increased in HCM and H-LVH groups; Compared to control and H-LVH group, Ej-EE were higher and IVC-vor-area, Ej-vor-area, IVS-LS were lower in HCM group (P<0.05). ② The“ reverse vortex” was observed significantly more frequently in the HCM group (HCM 88% vs H-LVH 16.7%, P<0.05). ③ Multiple linear regression analysis showed that IVC-vor-area and GLS could independently predict Ej-EE (P<0.05). Conclusion The abnormal hemodynamics and differences between HCM and H-LVH can be reflected by systolic blood EE and intra-ventricular vortex parameters. |
| Key words: Hypertrophic cardiomyopathy, hypertensive left ventricular hypertrophy, vortex, energy efficiency |
