| 摘要: |
| 目的 探究小剂量多巴酚丁胺负荷超声(LDDSE)联合心肌声学造影(MCE)对经皮冠脉介入(PCI)患者预后的评估价值。方法：选择2020年3月~2021年2月医院收治32例冠心病需行PCI手术患者作为研究对象。所有患者在PCI术前与PCI术后3个月、术后12个月均行LDDSE负荷超声及MCE检查,比较患者正常与坏死心肌手术前后灌注情况；随访评估患者预后,依据预后进行分组,比较预后不良及预后良好患者PCI术后3个月心肌灌注指标差异,并分析其对预后的预测价值。结果 坏死心肌位置MCE测定A、β、A×β值及LDDSE结合MCE测定A、β、A×β值等灌注指标均低于正常心肌(P＜0.05)；患者PCI术后3个月与12个月坏死心肌MCE测定A、β、A×β值及LDDSE结合MCE测定A、β、A×β值等灌注指标均高于PCI术前,同时低于正常心肌(P＜0.05),患者PCI术后3个月与12个月MCE测定A、β、A×β值及LDDSE结合MCE测定A、β、A×β值等心肌灌注指标比较没有统计学意义(P＞0.05)；预后不良患者PCI术后坏死心肌部位应用MCE测定A、β、A×β值及LDDSE结合MCE测定A、β、A×β值等灌注指标均低于预后良好(P＜0.05)；ROC曲线显示,MCE测定A、β、A×β值用于患者预后预测曲线下面积(AUC)值分别为0.682、0.710、0.712,LDDSE结合MCE测定A、β、A×β值AUC值分别为0.892、0.853、0.801。结论 LDDSE结合MCE可以反映PCI术后心肌微循环灌注情况,其用于患者预后预测价值优异。 |
| 关键词: 小剂量多巴酚丁胺负荷超声 心肌声学造影 经皮冠脉介入 预后 |
| DOI： |
| 投稿时间：2023-02-28修订日期：2023-03-21 |
| 基金项目: |
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| Prognostic value of myocardial perfusion measured by LDDSE combined with MCE in patients undergoing PCI |
| zhouqiping,wangliangyu,wangyin |
| () |
| Abstract: |
| Objective To investigate the prognostic value of low-dose dobutamine stress echocardiography (LDDSE) combined with myocardial contrast echocardiography (MCE) in patients undergoing percutaneous coronary intervention (PCI). Methods A total of 32 patients with coronary heart disease who underwent PCI in the hospital from March 2020 to February 2021 were selected as the research subjects. All patients underwent LDDSE and MCE before PCI and at 3 months and 12 months after PCI. Perfusion of normal and necrotic myocardium was compared before and after operation. The patients were grouped according to the prognosis. Myocardial perfusion indicators were compared between patients with poor prognosis and patients with good prognosis at 3 months after PCI. The prognostic value of these indicators was analyzed. Results The A, β and A×β values measured by MCE alone and by LDDSE combined with MCE at the necrotic myocardium were lower than those of normal myocardium (P<0.05). The A, β and A×β values measured by MCE alone and by LDDSE combined with MCE at the necrotic myocardium at 3 months and 12 months after PCI were higher than those before PCI, and lower than those of normal myocardium (P<0.05). There was no statistically significant difference in A, β and A×β values measured by MCE alone and by LDDSE combined with MCE at 3 months and 12 months after PCI (P>0.05). After PCI, the A, β and A×β values measured by MCE alone and by LDDSE combined with MCE at the necrotic myocardium were lower in patients with poor prognosis than those with good prognosis (P<0.05). The receiver operating characteristic (ROC) curve analysis showed that the area under the curve (AUC) values of A, β and A×β values measured by MCE alone for prognosis were 0.682, 0.710 and 0.712. The AUC values of A, β and A×β values measured by LDDSE combined with MCE were 0.892, 0.853 and 0.801. Conclusion LDDSE combined with MCE can reflect myocardial microcirculation perfusion after PCI, and can be used for prognosis. |
| Key words: Low-dose dobutamine stress echocardiography Myocardial contrast echocardiography Percutaneous coronary intervention Prognosis |
