The myocardium of patients with diabetes mellitus (DM) and early DM can be damaged to varying degrees. Timely detection of changes in cardiac structure and function of DM patients is of great significance for effective treatment of DM patients and prevention of DCM. As a non-invasive new technology, ultrasonic speckle tracking imaging (STI) can provide more sensitive and accurate cardiac function evaluation for patients with DM, especially the systolic and diastolic function evaluation of left atrium and left ventricle. This paper reviews the application progress of STI technology in the evaluation of left atrial and left ventricular function in patients with DM.