| 摘要: |
| 自身抗体相关的先天性心脏传导阻滞与母体抗干燥综合征抗原A、抗干燥综合征抗原B抗体阳性均相关，该病病情进展迅速，严重的房室传导阻滞患儿死亡率较高，大多患儿需植入永久起搏器，早期诊断对改善患儿预后具有重要意义。本文就自身抗体对心脏和传导系统的影响及自身抗体相关的先天性心脏传导阻滞宫内超声诊断的研究进展进行综述。 |
| 关键词: 超声心动描记术 胎儿 先天性心脏传导阻滞 抗SSA抗体 抗SSB抗体 |
| DOI： |
| 投稿时间：2023-04-18修订日期：2023-11-25 |
| 基金项目: |
|
| Research progress on prenatal ultrasound diagnosis of autoantibody-associated congenital heart block |
| Gao Yipeng,Deng Youbin |
| (Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology) |
| Abstract: |
| Autoantibody-associated congenital heart block is associated with maternal positivity for anti-SSA and anti-SSB antibodies. The disease progresses rapidly，and the mortality rate for severe atrioventricular block is high. Most affected infants require permanent pacemaker implantation，and early diagnosis is of great importance for improving fetal prognosis. This review aims to explore the effects of autoantibodies on the heart and conduction system，as well as the research progress on prenatal ultrasound diagnosis of congenital heart block related to autoantibodies. |
| Key words: Echocardiography Fetus Congenital heart block Anti-SSA antibodies Anti-SSB antibodies |
