Objective To investigate the blood flow characteristics of the central retinal artery(CRA) in the postcerebral infarction phase. And to analysis its correlation with vascular cognitive impairment (VCI).Methods Ninety-five patients with sequelae of cerebral infarction were included as a case group,and 77 healthy volunteers were included as a control group.The subjects'' cognitive functions(categorized according to the scores: mild coginitive impairment(MCI) and dementia(VaD) were evaluated using the Brief Mental State Examination(MMSE).Plane wave ultrasensitive flow imaging(Angio PLUS) was applied to explore each flow parameter of CRA,and the flow characteristics and differences of CRA in the case and control groups were analyzed.The correlation between CRA and VCI was analyzed according to whether the patients developed VCI and VCI grades.Results There was no statistically significant difference in age,gender,education level,hyperlipidemia,smoking and alcohol consumption between the two groups(all P>0.05),the difference in diabetes,hypertension and BMI was statistically significant(all P<0.05).Correlation analysis showed that there was a significant correlation between each blood flow parameter of CRA and whether or not VCI occurred and VCI score,which was positively correlated.The VCI score was negatively correlated with the EDV in the case group(r=-0.240,P=0.020) and negatively correlated with the RI(r =0.213,P<0.05).Conclusion CRA has certain blood flow characteristics in the postinfarction phase of cerebral infarction. And there is some correlation between CRA and VCI CRA may be a potential biomarker for intensive VCI research.