| 摘要: |
| 摘 要 目的 探讨经腹联合经会阴超声检查对克罗恩病评估的应用价值。方法 选取我院收治的克罗恩病患者87例，均行经腹超声联合经会阴超声检查，观察空回肠及结直肠的肠壁厚度、肠壁血流分级、肠道弹性成像值、肠外并发症情况；肠镜检查肠壁炎症程度并进行SES-CD评分及组织学活检；实验室检查收集患者超敏C反应蛋白浓度。分析各超声参数与肠镜检查结果、C反应蛋白的相关性。结果 本研究87例CD患者中，同时进行超声及肠镜检查的肠段共计435个。肠镜检查提示缓解期肠段326个（74.94%），活动期肠段109个（25.06%）。其中末段回肠受累者59.8%（52/87）处于活动期。相关分析显示，肠壁厚度、Limberg血流分级均与SES-CD分期呈高度正相关（r=0.796、0.742，均P＜0.001）；末段回肠肠壁厚度、Limberg血流分级分别与超敏C反应蛋白呈中度正相关、弱正相关（r=0.496、0.399，均P＜0.05）；各肠段SWE值与SES-CD评分无相关性。结论 经腹联合经会阴肠道超声能够清晰显示克罗恩病患者的肠道病变及肠外并发症，可以较准确地评估病变的活动度，有一定的临床价值。 |
| 关键词: 超声检查，经腹部，经会阴 克罗恩病 |
| DOI： |
| 投稿时间：2023-09-29修订日期：2024-03-20 |
| 基金项目: |
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| Application of transabdominal combined with transperineal ultrasound in the management of Crohn’s disease |
| xi Fen |
| () |
| Abstract: |
| ABSTRACT Objective To evaluate the efficacy of transabdominal combined with transperineal ultrasonography in assessing Crohn''s disease. Methods A total of 87 patients with Crohn''s disease admitted to our hospital were examined by transabdominal ultrasonography combined with transperineal ultrasonography. The thickness of intestinal wall, intestinal wall blood flow grading, intestinal elastic imaging value and parenteral complications were observed. The degree of intestinal wall inflammation was examined by colonoscopy and SES-CD score and histological biopsy were performed. The concentration of hypersensitive C-reactive protein was collected by laboratory examination. The correlation of ultrasonic parameters with colonoscopy results and C-reactive protein was analyzed. Results In this study, a total of 435 intestinal segments were examined using ultrasound and colonoscopy in 87 patients with CD. The colonoscopy results showed that 326 (74.94%) intestinal segments were in the remission stage, while 109 (25.06%) were in the active stage. Among these active segments, 59.8% (52/87) were located in the terminal ileum. Correlation analysis revealed that there was a strong positive correlation between intestinal wall thickness and Limberg blood flow grade with SES-CD stage (r=0.796, 0.742, P < 0.001). The thickness of the ileum wall and Limberg blood flow grade were moderately positively correlated with hypersensitive C-reactive protein (r = 0.496, 0.399, both P < 0.05). However, no correlation was observed between SWE value and SES-CD score. Conclusion Transabdominal combined transperineal intestinal ultrasound provides clear visualization of intestinal lesions and parenteral complications in patients with Crohn''s disease. It offers an accurate evaluation of the level of lesion activity, thus holding significant clinical value. |
| Key words: transabdominal ultrasound Transperineal ultrasound Crohn |
