| 摘要: |
| 目的 探讨常规超声测量全胃容积（VWS）评估糖尿病患者胃容受功能的临床价值，分析其相关影响因素。方法 选取我院121例糖尿病患者（糖尿病组）和99例健康志愿者（健康对照组）。均于饮入500 ml温水后应用超声扫查充盈后的胃腔，测量胃底最大切面面积、胃体短轴切面面积和长径、胃窦短轴切面面积和长径，并计算VWS。根据入组糖尿病患者的性别、年龄、BMI、空腹血糖（FPG）及糖化血红蛋白（HbA1c）水平进行分组，比较糖尿病组与健康对照组、不同临床资料的糖尿病患者间VWS相关超声测值的差异。分析VWS与性别、年龄、BMI、FPG及HbA1c的相关性。结果 糖尿病组与健康对照组比较：糖尿病组VWS为（516.03±73.42）cm3，健康对照组VWS为（679.23±96.25）cm3。糖尿病组胃底面积（FA）、胃体长径（BL）、胃体面积（BA）、胃窦面积（AA）、VWS均小于健康对照组，差异均有统计学意义（均P＜0.05）。不同临床资料的糖尿病患者比较：①与男性组比较，女性组FA、VWS均减小，差异均有统计学意义（均P＜0.05）；BL、BA、AL、AA比较，差异均无统计学意义。②不同FPG水平糖尿病患者FA、BA、VWS比较，差异均有统计学意义（均P＜0.05）。两两比较显示，与FPG＜7 mmol/L组、7 mmol/L≤FPG＜10 mmol/L组比较，FPG≥10 mmol/L组FA、BA、VWS均减小（均P＜0.05）；与FPG＜7 mmol/L组比较，7 mmol/L≤FPG＜10 mmol/L组FA、VWS均减小（均P＜0.05）。③不同年龄、BMI、HbA1c水平的糖尿病患者各超声测值比较，差异均无统计学意义。相关性分析显示，VWS与FPG呈负相关（rs=-0.411，P＜0.01），与性别、年龄、BMI及HbA1c无相关性。结论 常规超声测量VWS有望成为评估糖尿病患者胃容受功能的有效手段；糖尿病患者的VWS小于健康志愿者，且FPG是糖尿病患者VWS的主要影响因素。 |
| 关键词: 糖尿病 超声 胃容积 |
| DOI： |
| 投稿时间：2023-12-28修订日期：2024-06-09 |
| 基金项目:无 |
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| Preliminary exploration of the volume of the whole stomach measured by ultrasound in the assessment of gastric function in patients with diabetes mellitus |
| Yang Yin,Jiang Huan,Chen Peng,Dilimire·Abuliezi,Zhuang Hua |
| () |
| Abstract: |
| Objective To investigate the clinical value of the volume of the whole stomach（VWS） measured by conventional ultrasound in evaluating gastric accommodation function in patients with diabetes mellitus，and to analyze its related influencing factors.Methods 121 diabetic patients (diabetes group) and 99 healthy volunteers (healthy control group) in our hospital were selected.After drinking 500 ml warm water，the filled gastric cavity was examined by ultrasound scan.The maximum section area of gastric fundus，the short axis section area and long diameter of gastric body，and the short axis section area and long diameter of gastric antrum were measured，and VWS was calculated.According to the gender，age，BMI，fasting blood glucose (FPG) and hemoglobin a1c (HbA1c) levels of the enrolled diabetic patients，the differences of VWS related ultrasound values between the diabetic group and the healthy control group and the diabetic patients with different clinical data were compared.The correlation between VWS and gender, age, BMI, FPG and HbA1c was analyzed.Results The VWS of diabetic group was (516.03±73.42) cm3，and that of healthy control group was (679.23±96.25) cm3.Gastric fundus area (FA)，gastric body length diameter (BL)，gastric body area (BA)，gastric antrum area (AA)，and VWS in diabetic group were all lower than those in healthy control group，and the differences were statistically significant (all P ＜ 0.05).Comparison of diabetic patients with different clinical data: ① Compared with male group，FA and VWS in female group decreased，and the differences were statistically significant (all P ＜ 0.05); There was no significant difference in BL，BA，AL，and AA.② There were statistically significant differences in FA，BA，and VWS among diabetic patients with different FPG levels (all P ＜ 0.05).Compared with FPG ＜ 7 mmol/L group and 7 mmol/L≤FPG ＜ 10 mmol/L group，FA, BA，and VWS in FPG≥10 mmol/L group were decreased (all P ＜ 0.05).Compared with FPG ＜ 7 mmol/L group，FA and VWS in 7 mmol/L≤FPG ＜ 10 mmol/L group were decreased (all P ＜ 0.05).③ There was no significant difference in the ultrasonic measurements of diabetes patients with different age，BMI，and HbA1c levels. Correlation analysis showed that VWS was negatively correlated with FPG (rs=-0.411, P ＜ 0.01)，but had no correlation with gender，age，BMI，and HbA1c.Conclusions Conventional ultrasound measurement of VWS is expected to be an effective means to evaluate gastric accommodation in diabetic patients.The VWS of diabetic patients was lower than that of healthy volunteers，and FPG was the main influencing factor of VWS in diabetic patients. |
| Key words: Ultrasonography Volume of the whole stomach Diabetes mellitus |
