| 摘要: |
| 摘 要 目的 分析超声灰阶直方图测量计算的胰脾超声灰阶比（UGSR）的相关影响因素，评估超声定量诊断非酒精性脂肪性胰腺疾病（NAFPD）的临床价值。方法 选取于我院行腹部CT及超声检查的95例住院患者，根据平扫CT诊断标准分为NAFPD组（44例）和非NAFPD组（51例）。应用灰阶直方图测量受试者胰腺、脾脏感兴趣区（ROI）平均灰阶值，计算二者比值即为胰脾UGSR，收集受试者临床资料。采用单因素及多因素线性回归分析筛选胰脾UGSR的影响因素：绘制受试者工作特征（ROC）曲线评估胰脾UGSR 对NAFPD的诊断效能。结果 单因素分析显示，年龄、体质量指数（BMI）、血压、空腹血糖（FBG）、甘油三酯（TG）、总胆固醇（TC）、低密度脂蛋白（LDL）均为胰脾UGSR的重要影响因素（均P＜0.05）：多因素回归分析显示，BMI、FBG均为胰脾UGSR的独立影响因素（均P＜0.05）。ROC曲线分析显示，胰脾UGSR诊断NAFPD的曲线下面积为0.929（95%可信区间：0.858~0.972），以1.64为截断值，对应的灵敏度为 97.73%，特异度为88.24%。结论 超声灰阶直方图测量计算的胰脾UGSR对NAFPD具有良好的诊断效能，且BMI、FBG均为胰脾UGSR的独立影响因素。 |
| 关键词: 超声检查：灰阶直方图：超声灰阶比：非酒精性脂肪胰腺疾病 |
| DOI： |
| 投稿时间：2024-03-10修订日期：2024-08-31 |
| 基金项目: |
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| Clinical value of pancreas-spleen ultrasound gray scale ratio in the diagnosis of non-alcoholic fatty pancreas disease and related factors |
| bishiyu,lutianqi,zhoukang,yangxiuhua |
| () |
| Abstract: |
| ABSTRACT Objective To analyze the relevant influencing factors of the pancreatic-splenic ultrasound gray-scale ratio (UGSR) calculated from ultrasound gray-scale histogram measurements and to assess the clinical value of ultrasound quantitative diagnosis of non-alcoholic fatty pancreas disease (NAFPD). Methods: We selected 95 hospitalized patients who underwent abdominal CT and ultrasound at our hospital. Based on the CT diagnostic criteria, patients were divided into the NAFPD group (44 cases) and the non-NAFPD group (51 cases). Gray-scale histograms were used to measure the average gray-scale values of the pancreatic and splenic regions of interest (ROI), and the ratio of these values was calculated as the pancreatic-splenic UGSR. Clinical data of the patients were collected. Univariate and multivariate linear regression analyses were used to identify the influencing factors of pancreatic-splenic UGSR. Receiver operating characteristic (ROC) curves were plotted to evaluate the diagnostic performance of UGSR for NAFPD. Results: Univariate analysis indicated that age, body mass index (BMI), blood pressure, fasting blood glucose (FBG), triglycerides (TG), total cholesterol (TC), and low-density lipoprotein (LDL) were significant influencing factors of pancreatic-splenic UGSR (all P<0.05). Multivariate regression analysis showed that BMI and FBG were independent influencing factors of pancreatic-splenic UGSR (all P<0.05). ROC curve analysis revealed that the area under the curve for UGSR in diagnosing NAFPD was 0.929 (95% confidence interval: 0.858–0.972), with a cutoff value of 1.64, corresponding to a sensitivity of 97.73% and a specificity of 88.24%. Conclusion: The pancreatic-splenic UGSR, calculated from ultrasound gray-scale histogram measurements, demonstrates good diagnostic performance for NAFPD, and BMI and FBG are independent influencing factors of pancreatic-splenic UGSR. |
| Key words: Non-alcoholic fatty pancreas, Quantitative ultrasound diagnostic techniques, Gray scale histograms, Ultrasound grayscale ratio |
