| 摘要: |
| 目的 比较低频和高频灰阶超声及超声造影在肝脏浅表局灶性病变检出和定性诊断中的价值。方法 回顾性纳入了38名有肝脏浅表局灶性病灶的患者，共63个病灶，平均深度为0.82±0.13 cm（0~4.5 cm），纳入病灶在CT/MR上可见，分别使用低频凸阵探头（平扫频率3.0~5.0 MHz，造影频率2.0~3.0 MHz）和高频线阵探头（平扫频率6.0~9.0 MHz，造影频率5.0 MHz）对病灶进行常规灰阶扫查和超声造影，比较二者在病灶可见度、检出率、表征和初步定性诊断中的价值。结果 高频超声造影下病灶可见度和检出率均明显高于低频超声造影（P<0.001），高频超声造影多检出23个（23/63，36.5%）病灶。高频超声对肿瘤声晕、特征性增强模式、晚期廓清显示更加清晰（P<0.001）。高频超声造影用于病灶良恶性诊断的敏感度、准确度、阳性预测值分别为88.1%、69.8%和78.7%。结论 在肝脏浅表局灶性病变中增加使用高频探头能改善病灶的可见度和检出率，更好的显示肿瘤的特殊回声征象和增强模式，有利于对病变的定性诊断。 |
| 关键词: 高频超声 超声造影 肝局灶性病变 肝细胞癌 肝转移瘤 |
| DOI： |
| 投稿时间：2024-04-17修订日期：2024-05-17 |
| 基金项目:南京鼓楼医院临床研究专项资金项目-面上项目(2022-LCYJ-MS-24) |
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| Clinical value of high-frequency contrast enhanced ultrasound in detecting and diagnosing superficial focal liver lesions |
| HE YUHONG,WEN BAOJIE,YU PENGLI,WAN WENPING,KONG WENTAO |
| (Department of Ultrasound, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University) |
| Abstract: |
| Objective To compare the value of low-frequency and high-frequency grayscale/contrast-enhanced ultrasound (CEUS) in the detection and qualitative diagnosis for superficial focal liver lesions. Methods Thirty-eight patients with 63 superficial focal liver lesions were retrospectively included in our study. The mean target lesion depth was 0.82±0.13 cm (0-4.5 cm). Low-frequency convex array probe (gray scale: 3.0~5.0 MHz; CEUS: 2.0~3.0 MHz) and high-frequency linear array probe (gray scale: 6.0~9.0 MHz; CEUS: 5 MHz) were used to perform conventional B-mode ultrasound and CEUS for lesions identified by computed tomography (CT) and magnetic resonance imaging (MRI), respectively. We evaluate their value in lesion visibility score, detection rate, characterization and initial qualitative diagnosis. Results High-frequency CEUS obtained a higher visibility score and detection rate than low-frequency CEUS (P<0.001), and additionally detect 23 (23/63, 36.5%) lesions that were invisible on low-frequency CEUS. Besides, the display of tumor “halo” sign, typical enhancement patterns, and late wash-out was also more distinct on high frequency ultrasound (P<0.001). Conclusion High-frequency ultrasound significantly enhanced the lesion visibility score and detection rate for superficial focal liver lesions, and better displayed the specific echo signs and enhancement patterns of tumor, which is conducive to the qualitative diagnosis of target lesions. |
| Key words: high-frequency ultrasound contrast enhanced ultrasound focal liver lesion hepatocellular carcinoma liver metastasis |
