| 摘要: |
| 目的 探索四维左心房定量分析技术(4D-Auto-LAQ)评价隐匿性未控制高血压(MUHT)患者左心房功能早期变化的临床应用价值。资料与方法 选取24h动态血压监测的患者总计71例：根据血压情况分为MUHT组,血压控制良好(WCHT)组。采用4D-Auto-LAQ技术获得左心房容积参数:左房最大容积(LAVmax)、左房收缩前容积(LAVpre)、左房最小容积(LAVmin)并将其与体表面积标化后分别得到左房最大容积指数(LAVImax)、左房收缩前容积指数(LAVIpre)、左房最小容积指数(LAVImin)。分别计算左心房总射血分数(LAEF)、左心房被动射血分数(LApEF)、左心房主动射血分数(LAaEF)。左心房功能参数:左心房储备期应变(LASr)、左心房管道期应变(LAScd)、左心房收缩期应变(LASct)。结果 MUHT组左心房容积参数与WCHT组相比LAVImax、LAVIpre、LAVImin、LAaEF均增加,LApEF减低差异有统计学意义(P<0.05)。MUHT组左心房应变参数与WCHT组相比 LASr、LAScd、LASct均减低差异有统计学意义(P<0.05)。Pearson相关分析显示LASr与E/e’呈正相关(r=0.386,P=0.001),LAScd、LASct与E/e’无明显相关性(P>0.05)。结论 4D-Auto-LAQ技术可准确、方便提供左心房容积和应变参数,可以用于早期发现隐匿性未控制高血压患者左心房功能变化。 |
| 关键词: 隐匿性未控制高血压 左心房 四维左心房定量分析技术 |
| DOI： |
| 投稿时间：2024-04-28修订日期：2024-06-19 |
| 基金项目: |
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| Evaluation of left atrium function in patients with masked uncontrolled hypertension by 4D-Auto-LAQ technology |
| Li Ying,Sun Xuechun,Zhao Hanzhang,Li Jing,Zhang Huihui,Ding Mingyan |
| (Department of Cardiac Function,People’s Hospital of Liaoning Province) |
| Abstract: |
| Objective Exploring the clinical value of 4D-Auto-LAQ technology in evaluating early changes of left atrium function in patients with masked uncontrolled hypertension. Methods A total of 71 patients were selected for 24-h ambulatory blood pressure,based on the blood pressure the patients were divided into two groups: masked uncontrolled hypertension group (MUHT) and well-controlled hypertension group (WCHT) . We obtained left atrial volume parameters by 4D-Auto-LAQ: left atrium maximum volume (LAVmax) , left atrium pre-contraction volume (LAVpre) , left atrium minimum volume (LAVmin). After standardized with the body surface area we gained left atrium maximum volume index (LAVImax) , left atrium pre-contraction volume index (LAVIpre), left atrium minimum volume index (LAVImin). Then calculating left atrial emptying function: left atrial total emptying function (LAEF), left atrial passive emptying function (LApEF), left atrial active emptying function(LAaEF). Results Compared with the WCHT group, the left atrial parameters of the MUHT group had a significant increase in LAVImax, LAVIpre, LAVImin, LAaEF and reduce in LApEF (all P<0.05). The left atrial strain parameters of LASr、LAScd、LASct in the MUHT group were significantly lower than those in the WCHT group (all P<0.05). Pearson correlation analysis showed that LASr was positively correlated with E/e’ (r = 0.386, P=0.00), LAScd and LASct were not correlated with E/e’(P>0.05). Conclusion 4D-Auto-LAQ is an accurate and convenient technology in the measurement of left atrial volume and strain parameters, which can detect the early changes of left atrium function in patients with masked uncontrolled hypertension. |
| Key words: masked uncontrolled hypertension left atrium Four-dimensional quantitative analysis of left atrium |
