| 摘要: |
| 目的:探究超声造影定性及定量技术对继发性甲状旁腺功能亢进(SHPT)病情程度评估及微波消融术后复发的预测价值。方法:回顾性分析2021年1月-2023年8月我院就诊75例SHPT患者临床资料,所有患者入院后均采用超声造影定性技术评估其灌注模式、增强早晚、增强均匀性、最早到达时间、峰值强度(PI)及行程时间。依据血清甲状旁腺激素(PTH)水平将患者分为轻(PTH在250~600ng/L)、中(PTH在600~800ng/L)、重(PTH＞800ng/L)3组,对比3组患者超声造影定性技术检测结果,依据PI检测值绘制ROC曲线,分析超声造影定性及定量技术对SHPT患者微波消融术后复发的预测效能。结果:3组灌注模式、增强均匀、最早到达时间比较差异有统计学意义(P＜0.05),增强早晚、行程时间比较差异无统计学意义(P＞0.05)。复发组与未复发组增强均匀、PI比较差异有统计学意义(P＜0.05),灌注模式、增强早晚、行程时间、最早到达时间比较差异无统计学意义(P＞0.05)。ROC曲线分析结果,PI值预测代SHPT患者微波消融术后复发的曲线下面积(AUC)为0.631(P＜0.05)。结论:超声造影定性技术可用于评估SHPT患者病情程度,且PI值对SHPT患者微波消融术后复发均具有较高的预测价值。 |
| 关键词: 超声造影 继发性甲状旁腺功能亢进 预测价值 |
| DOI： |
| 投稿时间：2024-05-30修订日期：2024-06-28 |
| 基金项目: |
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| Preventive value of contrast-enhanced ultrasound on postoperative recurrence of secondary hyperparathyroidism |
| chenjieneng,xiebin,zhaoxianwei,zhangyumin,huanghao |
| () |
| Abstract: |
| Objective: To explore the predictive value of qualitative and quantitative techniques of contrast-enhanced ultrasound on evaluating the severity of secondary hyperparathyroidism (SHPT) and the recurrence after microwave ablation. Methods: The clinical data of 75 patients with SHPT treated in our hospital from January 2021 to August 2023 were retrospectively analyzed. After admission, qualitative technique of contrast-enhanced ultrasound was used to assess the perfusion pattern, early and late enhancement, enhancement uniformity, earliest arrival time, peak intensity (PI) and travel time. The patients were divided into mild group (PTH between 250ng/L and 600ng/L), moderate group (PTH between 600ng/L and 800ng/L) and severe group (PTH>800ng/L) according to serum parathyroid hormone (PTH) level. The detection results of qualitative technique of contrast-enhanced ultrasound were compared among the three groups, and ROC curve wad drawn according to the PI detection to analyze the predictive efficiency of qualitative and quantitative techniques of contrast-enhanced ultrasound on recurrence after microwave ablation in patients with SHPT. Results: There were statistically significant differences in perfusion pattern, enhancement uniformity and earliest arrival time among the three groups (P<0.05), but there were no statistical differences in early and late enhancement and travel time (P>0.05). The enhancement uniformity and PI revealed statistical differences between recurrence group and non-recurrence group (P<0.05), but the perfusion pattern, early and late enhancement, travel time and earliest arrival time were not statistically different between the two groups (P<0.05). ROC curve analysis showed that the area under the curve (AUC) of PI value on predicting recurrence in patients with SHPT after microwave ablation was 0.631 (P<0.05). Conclusion: Qualitative technique of contrast-enhanced ultrasound can be used to evaluate the severity of patients with SHPT, and PI value has a high predictive value on the recurrence in patients with SHPT after microwave ablation. |
| Key words: Contrast-enhanced ultrasound Secondary hyperparathyroidism Predictive value |
