:Objective To investigate the value of left atrial strain and left atrial appendage emptying? velocity in predicting early recurrence after ablation of persistent atrial fibrillation.Methods A prospective study of 122 patients with persistent atrial fibrillation (PeAF) undergoing catheter ablation in Bozhou People"s Hospital from October 2022 to February 2024. After 3-month follow-up, 74 patients were divided into two groups (recurrence group and non-recurrence group according to the follow-up results). Complete demographic information was collected before ablation, including gender, age, body mass index, duration of disease, comorbidities and laboratory indicators NT-ProBNP. On the day of AF ablation, maintaining sinus rhythm, preoperative transthoracic echocardiogram (TTE) and transesophageal echocardiography (TEE) images were collected for left ventricular end-diastolic diameter (LVEDD), left atrial diameter (LAD), biplane left volume index (LAVI), left atrial ejection fraction (LAEF), ejection fraction (LVEF), left ventricular ejection fraction (LVEF). The E peak of the mitral valve, the mean e "value of the mitral valve ring of the Doppler chamber to calculate E / e", and the TEE to obtain the maximum emptying velocity of the left atrial appendage (LAAeV). Two-dimensional speckle tracking technology acquired the left ventricular global longitudinal strain (LVGLS), Left atrial reservoir strain (LASr),Left atrial conduit strain (LAScd), and left atrial pump strain (LASct). Results 78 patients 26 patients with recurrence within 3 months, and 48 patients without recurrence showed the difference between relapse group and no recurrence group (P>0.05), while the difference in laboratory index NT-proBNP was statistically significant, and the recurrence group was greater than the non-relapse group (P <0.05). For the comparison of conventional echocardiographic parameters between the two groups, there was no significant difference in LVEDD, E / e ", LVEF, and LAEF (P>0.05), but LAD, LAVI, and LAAeV (P<0.05), and LASr, LASct, and LVGLS were lower than the nonrelapse group, respectively (P<0.05), and LAScd (P>0.05). In univariate and multivariate binary Logistic regression analysis, NT-proBNP, LVGLS, LAVI, LASr, LASct and LAAeV were risk factors for early recurrence after PeAF ablation, and LASr, LASct and LAAeV were independent risk factors for early recurrence after PeAF ablation. Further ROC curve analysis showed that the area under the curve for LASr, LASct, and LAAeV was 0.821,0.709, and 0.839, respectively. The area under the combined prediction curve of the three was 0.938 (P<0.001).Conclusion NT-proBNP, LVGLS, LAVI, LASr, LASct and LAAeV are risk factors for early recurrence after PeAF ablation, among which LASr, LASct and LAAeV are independent predictors of early recurrence after PeAF ablation, and left atrial strain function combined with LAAeV has some application value in predicting early recurrence after PEAF ablation.