Myocardial fibrosis (MF) can be seen in various heart diseases and is associated with poor prognosis. Endocardium biopsy is the gold standard for detection of myocardial fibrosis, but its wide clinical application is limited due to its invasive nature. Echocardiography, as a non-invasive and convenient imaging technique, can provide non-invasive diagnostic information for myocardial fibrosis and is of great significance for evaluating myocardial fibrosis. This article reviewed the application and research progress of echocardiography in evaluating myocardial fibrosis.